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Diabetes & Endocrinology

Mortality and Morbidity After Below-Knee Amputation in Diabetes: Insights from a 25-Year English Cohort Study

MedXY Editorial TeamSep 17, 2026
diabetesbelow-knee amputationreamputationcomorbidity

Highlight

Below-knee amputation (BKA) in people with diabetes is associated with substantial mortality, showing no improvement over the past decade. One-year mortality stands at 23.5% and rises dramatically to over 82% at 10 years. Older age, female sex, and a higher burden of comorbidities independently increase mortality risk post-BKA. Additionally, 90-day postoperative complications remain frequent, underscoring the complex clinical challenges of advanced diabetic foot disease.

Study Background and Disease Burden

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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