Section
A thorough secondary analysis of a randomized clinical trial reveals no significant association between cornea donor diabetes severity and graft success, endothelial cell loss, or morphometric parameters at 1 year post-DMEK, supporting the
Continuous glucose monitoring-guided insulin optimization improves glycemic control and nutritional status in insulin-treated adults receiving long-term nocturnal parenteral nutrition, reducing hyperglycemia and associated complications.
A novel CGM-derived disposition index reliably estimates beta cell function in individuals with islet autoimmunity without insulin therapy, predicting glycemic deterioration one year later.
This study clarifies that the metabolic risks linked to fat-free mass are largely dependent on visceral and muscle fat infiltration, not FFM alone, highlighting the need for nuanced assessment in metabolic syndrome risk.
This study explores how the choice of diabetes self-care location at school affects glycemic control in children with Type 1 diabetes, highlighting restroom use as a risk factor for poorer outcomes and emphasizing the need for supportive sc
This study demonstrates that polygenic risk scores (PRS) independently predict type 2 diabetes risk in Japanese individuals, and healthy lifestyles can mitigate this risk even among genetically predisposed people, enhancing personalized pre
This review synthesizes evidence demonstrating that continuous glucose monitoring (CGM) metrics, particularly time above 140 mg/dL, predict progression to stage 3 type 1 diabetes with accuracy comparable to oral glucose tolerance test (OGTT
This report describes two siblings with 46,XY DSD caused by novel biallelic CYB5A variants including a missense and a deep intronic mutation disrupting splicing, expanding knowledge of CYB5A-related disorders.
This two-center randomized trial assessed near-infrared autofluorescence imaging to identify parathyroid glands during total thyroidectomy. Despite higher gland identification rates, the technology did not reduce hypoparathyroidism incidenc
A national cohort study reveals significant gaps in the diagnosis and pharmacologic treatment of adults with laboratory-confirmed diabetes, highlighting the impact of glycemic severity and comorbidities on care delivery.
GLP-1 receptor agonists are increasingly used in women of reproductive age, but their safety during periconception and pregnancy remains unclear. Current observational data show no definitive harm, yet robust evidence is lacking, emphasizin
This study reveals distinctive trajectories of BMI, body roundness, and muscle strength surrounding type 2 diabetes diagnosis, highlighting complex body composition changes including pre-diagnosis weight peaks, persistent visceral fat, and
This study compares the environmental impacts of three offloading treatments for plantar foot ulcers in diabetes, finding removable walkers to be the most sustainable option.
Prolactinomas, common pituitary adenomas in reproductive-age women, challenge pregnancy management due to risks of tumor growth and hormonal shifts. This article reviews current strategies for diagnosis, treatment, and monitoring before, du
Functional hypothalamic amenorrhea (FHA) in mid-adulthood is linked to increased coronary heart disease risk and type 2 diabetes, independent of traditional factors, highlighting menstrual irregularities as early cardiometabolic risk indica
This study reveals that the reduced risk of type 1 diabetes in children born to mothers with the condition is not due to genetic differences but possibly to protective intrauterine exposures during early childhood.
A randomized trial demonstrates that adding the digital therapeutic glucura to intermittent CGM and standard care significantly improves HbA1c, weight loss, and mental health in non-insulin-treated type 2 diabetes patients over six months.
This study reveals how liver-sourced apolipoprotein J worsens diabetic kidney disease by impairing lipid regulation via TFEB pathways, highlighting a novel therapeutic target, MK53, for managing diabetic renal injury.
This study reveals that many patients with primary aldosteronism have inappropriately normal aldosterone levels and shows that modifying the aldosterone-to-renin ratio improves sensitivity in diagnosis without compromising specificity.
A 50-year-old woman with metastatic medullary thyroid carcinoma (MTC) lacking RET alterations exhibited a remarkable sustained response to selpercatinib, suggesting potential efficacy beyond RET-mutated cases.
