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The Bone Health Index (BHI), derived from metacarpal radiographs, predicts fracture risk more effectively than DXA in children with Osteogenesis Imperfecta, especially infants under five where DXA is limited.
This study evaluates complication rates following body contouring after weight loss via bariatric surgery, GLP-1 receptor agonists, combination therapy, and lifestyle changes, finding weight-loss modality does not affect postoperative compl
PMOS reframes polycystic ovary syndrome as a systemic endocrine-metabolic disorder with lifelong implications, emphasizing the need for comprehensive obstetric and gynecologic care to improve diagnosis, pregnancy outcomes, and long-term hea
Detection of genomic alterations via Afirma Xpression Atlas in indeterminate thyroid nodules enhances malignancy risk stratification beyond Afirma GSC results, guiding surgical decision-making.
This study demonstrates that urinary aldosterone measurement by LC-MS/MS outperforms immunoassay in diagnosing primary aldosteronism, especially when urinary sodium is within an optimal range, offering improved sensitivity and specificity f
This prospective cohort study compares semaglutide, bariatric surgery, and lifestyle therapy in obese patients with MASLD, demonstrating semaglutide and surgery improve liver steatosis and fibrosis markers better than lifestyle changes alon
The DASH4D diet, a tailored DASH-style intervention for diabetes, significantly improved key glycemic biomarkers including fructosamine, fasting glucose, and HbA1c compared to a typical American diet in adults with type 2 diabetes.
Weekly well-day capillary ketone testing maintains predictive accuracy for 1-month diabetic ketoacidosis risk, offering a practical and less burdensome monitoring strategy for patients with type 1 diabetes.
Third-trimester energy restriction in women with gestational diabetes and elevated BMI does not adversely affect infant growth or body composition through the first postnatal year, suggesting safety of modest maternal weight loss in late pr
This article explores ethical dilemmas in pediatric endocrinology through case studies, applying the four-principle framework to guide clinicians in managing complex patient scenarios effectively and compassionately.
A comprehensive multicenter study reveals frequent neuroimaging abnormalities in children with Noonan syndrome and elucidates their associations with genetic variants and neurological symptoms, enhancing understanding of brain involvement i
Adults with type 1 diabetes face substantial financial toxicity and cost-related nonadherence, especially younger adults, underscoring the need for targeted interventions beyond traditional social determinants of health.
A clear, clinician-focused summary of the 2025 VA/DoD guideline update: new screening thresholds, streamlined treatment pathways, integration of pharmacotherapy (including GLP‑1 receptor agonists), endoscopic and surgical options, and veter
This phase 2b trial evaluates bofanglutide’s efficacy and safety compared to semaglutide in Chinese patients with type 2 diabetes, showing notable HbA1c reductions and manageable gastrointestinal side effects.
Elevated plasma pro-opiomelanocortin (POMC) levels accurately predict silent corticotroph adenomas (SCAs) among clinically non-functioning pituitary adenomas, offering a promising tool for diagnosis and monitoring.
This study evaluates teprotumumab’s effectiveness for thyroid eye disease in Japanese patients, revealing notable improvements in orbital inflammation and proptosis compared to intravenous glucocorticoid therapy with distinct MRI-base
The gain-of-function GLP1R R131Q variant slows β-cell decline and improves glycemic response to GLP-1 receptor agonists, highlighting its potential role in precision diabetes therapeutics.
A randomized controlled trial demonstrates that PTeye-guided near-infrared autofluorescence significantly improves identification and preservation of parathyroid glands during total thyroidectomy, reducing transient hypoparathyroidism, espe
This study maps apo AI glycation sites in diabetes, linking them to HDL dysfunction and diabetic atherosclerosis via RAGE-associated signaling, and demonstrates that glycation-resistant apo AI preserves HDL function and lessens atherosclero
Women with preconception hemithyroidectomy face a substantially increased risk of overt hypothyroidism during pregnancy, especially after thyroid cancer surgery, yet obstetric outcomes remain comparable to women with intact thyroids.
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