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This post hoc analysis of the PREVENT trial highlights that preventive PCI significantly reduces adverse cardiac events in patients with vulnerable lipid-rich plaques, identified by near-infrared spectroscopy, underscoring the importance of
Occupational exposure to both dust and fumes significantly increases the risk of future respiratory exacerbations, atherosclerotic cardiovascular disease, and pneumonia in smokers and former smokers, underscoring the need for targeted preve
Early catheter ablation in atrial fibrillation patients with prior ischemic stroke reduces major adverse cardiovascular events and improves neurological and cognitive outcomes compared to medical therapy, according to a multi-center retrosp
Functional hypothalamic amenorrhea (FHA) in mid-adulthood is linked to increased coronary heart disease risk and type 2 diabetes, independent of traditional factors, highlighting menstrual irregularities as early cardiometabolic risk indica
This study reveals that syndecan-4 shedding exacerbates deep vein thrombosis by promoting Piezo1-dependent endothelial-mesenchymal transition, with quercetin showing promise as a novel therapeutic Piezo1 inhibitor.
Adult congenital heart disease (ACHD) patients now outnumber affected children, shifting focus to lifelong management. Advances in specialized care, health systems, and digital innovations offer promising models to improve outcomes and equi
A clear, clinician-focused summary of the 2026 EAPCI/EBC consensus recommending routine intravascular imaging (IVUS/OCT) to plan, guide and optimize left main bifurcation PCI — with practical steps, controversies and implementation advice.
Genetic analyses reveal that cholesteryl ester transfer protein (CETP) inhibition, while beneficial for cardiovascular disease, is associated with an increased risk of age-related macular degeneration (AMD) across European and East Asian po
This meta-analysis consolidates data from six RCTs comparing left atrial appendage closure (LAAC) to oral anticoagulation for stroke prevention in atrial fibrillation, highlighting reduced bleeding with LAAC but increased ischemic stroke ri
An indirect comparison shows tirzepatide significantly reduces major adverse cardiovascular events and mortality in type 2 diabetes patients, highlighting its potential for improving cardiovascular outcomes.
The SWEDEGRAFT trial reveals no significant difference in 7-year major clinical outcomes between no-touch and conventional saphenous vein harvesting in CABG, despite prior reports of improved graft patency but increased leg wound complicati
Most heart failure patients harbor multiple cardiovascular-kidney-metabolic conditions, which independently escalate mortality and readmission risk, especially in HFrEF, underscoring the need for integrated management strategies tailored by
HEARTBiT, a novel transcriptomic biomarker, effectively detects moderate-to-severe acute cellular rejection within the first year after heart transplantation, offering a minimally invasive alternative to biopsy, especially during the high-r
A practical, clinician-focused summary of the 2026 European Heart Journal consensus on implementing cardiac magnetic resonance (CMR) across common cardiac diseases, highlighting indications, protocols, prognostic use, device safety, and wor
SMOC-1, secreted by cardiomyocytes after acute myocardial infarction, supports fibrosis and scar formation, reducing cardiac rupture risk. Enhancing this pathway offers promising therapeutic potential.
National data show that Comprehensive Stroke Center status and trial participation independently predict reported stroke rates after TAVR, highlighting potential ascertainment bias affecting hospital performance metrics.
An epigenome-wide study reveals that DNA methylation markers linked to inflammatory pathways and blood lipid traits play a causal role in abdominal aortic aneurysm development, offering potential for improved risk prediction and therapeutic
Two large randomized trials reveal that testosterone therapy improves sexual function and mood without increasing cardiovascular risks in men with age-related low testosterone, but does not enhance vitality or physical function.
A nationwide prospective study shows no significant difference in survival or neurological outcomes between lidocaine and amiodarone for adult in-hospital cardiac arrest patients with refractory ventricular fibrillation or pulseless ventric
In the SELECT trial, baseline clinical factors poorly predicted peak body weight loss with semaglutide, highlighting the role of sex and dosage but underscoring substantial unexplained variability in patient response.
