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Elevated baseline CRP levels in older acute HF patients identify those who gain the most physical function improvement from a 12-week rehabilitation program, supporting biomarker-guided therapy.
The DASH4D diet, a diabetes-adapted version of the DASH eating plan, significantly improves blood pressure and blood sugar control in type 2 diabetes with hypertension, offering a strong evidence-based dietary recommendation for personalize
This study reveals that familial hypercholesterolaemia accelerates thymic ageing, reducing thymic output and altering T-cell diversity; statin therapy partially preserves thymic function, suggesting integrated metabolic-immunologic manageme
This study examines how effective patient-centered communication by physicians at community health centers supports self-management behaviors in patients with cardiometabolic conditions.
Elevated soluble ST2 worsens fulminant myocarditis by impairing cardiomyocyte mitochondria via IGF2R-YY1, providing a new prognostic biomarker and therapeutic target.
The DECISION trial demonstrated that discontinuation of low-dose digoxin in heart failure patients optimized on guideline therapy leads to increased heart failure events and clinical deterioration, supporting cautious withdrawal decisions.
This UK prospective study assesses pregnancy outcomes in women with preexisting cardiomyopathy, revealing generally favorable maternal and neonatal results with low cardiac complication rates and no maternal deaths.
This study reveals significant racial differences in atherosclerotic cardiovascular disease risk among women with PMOS, highlighting that social determinants of health influence these disparities, particularly among Black women.
The ICare-FASTER trial demonstrates that implementing point-of-care high-sensitivity cardiac troponin testing in emergency departments safely reduces patient length of stay by nearly 50 minutes without compromising 30-day cardiac safety out
This article explores how baseline aldosterone concentrations influence the efficacy and outcomes of mineralocorticoid receptor antagonists (MRAs) in heart failure patients, highlighting the need for tailored therapeutic approaches.
Incorporating pregnancy-related factors, especially hypertensive disorders of pregnancy, significantly improves the prediction of 10-year incident hypertension risk in women after their first childbirth, potentially guiding targeted cardiov
Genetic variants in dilated cardiomyopathy confer differential arrhythmic risks, independent of traditional clinical parameters. Integrating recent registry data and molecular studies enhances risk stratification and informs tailored manage
Transseptal transcatheter mitral valve replacement with the SAPIEN M3 system in patients with symptomatic mitral annular calcification shows sustained mitral regurgitation reduction, improved functional status, and meaningful quality-of-lif
This secondary analysis of the ANH trial found no significant reduction in allogeneic blood transfusions with acute normovolemic hemodilution in female cardiac surgery patients, but noted increased intraoperative hypotension and longer ICU
This cohort study links postpartum blood pressure at 6 weeks following hypertensive pregnancy disorders with a doubled risk of future cardiovascular disease, highlighting a crucial preventive care window.
The 2026 Second Universal Definition standardizes HF terminology, reframes ejection-fraction categories, formalizes pre-HF and dynamic HF trajectories, and offers a global, cause-based classification to improve prevention, diagnosis, resear
This review synthesizes evidence supporting outpatient management of acute low-risk pulmonary embolism (PE), highlighting risk stratification tools, safety outcomes, and implementation strategies to enhance adoption in clinical practice.
This study establishes transthyretin amyloid cardiomyopathy-specific mitral regurgitation thresholds, revealing lower severity cutoffs than guidelines and enhancing mortality and heart failure hospitalization risk prediction.
The 2026 EAPCI–ACVC consensus refines use of temporary mechanical circulatory support in acute myocardial infarction with cardiogenic shock, emphasizing phenotype-driven device selection, SCAI/SHARC staging, multidisciplinary shock teams an
A subcutaneous furosemide minipump-enabled early discharge strategy improves days alive and out of hospital in heart failure patients, reducing inpatient stay without increasing serious adverse events significantly.
