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Evaluating AI-Led vs Human-Led Lifestyle Interventions in Prediabetes: Evidence from a Randomized Clinical Trial of the Diabetes Prevention Program
AIartificial intelligencediabetes

Evaluating AI-Led vs Human-Led Lifestyle Interventions in Prediabetes: Evidence from a Randomized Clinical Trial of the Diabetes Prevention Program

By MedXY|Oct 29, 2025

This review examines the first phase 3 randomized trial demonstrating that an AI-powered Diabetes Prevention Program lifestyle intervention is noninferior to human coaching in improving weight loss, HbA1c, and physical activity among adults

Harnessing Cancer-Testis Antigens for Precision Immunotherapy in Head and Neck Cancer
AIHead and Neck Squamous Cell Carcinomaimmunotherapy

Harnessing Cancer-Testis Antigens for Precision Immunotherapy in Head and Neck Cancer

By MedXY|Oct 24, 2025

This study identifies specific cancer-testis antigens (CTAs) as promising targets for personalized immunotherapy in head and neck squamous cell carcinoma (HNSCC), validated across multiomic datasets to enhance therapeutic precision.

Harnessing Wearable Technology to Boost Cardiac Rehabilitation Adherence in CHD Patients: Insights from a Randomized Trial
AIadherenceCoronary heart disease

Harnessing Wearable Technology to Boost Cardiac Rehabilitation Adherence in CHD Patients: Insights from a Randomized Trial

By MedXY|Oct 23, 2025

This study evaluates how smartwatch-assisted home-based cardiac rehab improves exercise adherence and health outcomes in coronary heart disease patients.

Revolutionizing Cardiac Rehab: The Impact of Wearable Technology and Online Coaching
AIcoronary artery diseaseremote monitoring

Revolutionizing Cardiac Rehab: The Impact of Wearable Technology and Online Coaching

By MedXY|Oct 23, 2025

This review discusses a landmark study demonstrating how wearable devices and online coaching improve exercise capacity in coronary artery disease patients, highlighting advancements in remote cardiac rehabilitation.

Artificial Intelligence in Imaging-Based Extranodal Extension Detection: Advancing Prognostication in HPV-Positive Oropharyngeal Cancer
AIartificial intelligenceExtranodal Extension

Artificial Intelligence in Imaging-Based Extranodal Extension Detection: Advancing Prognostication in HPV-Positive Oropharyngeal Cancer

By MedXY|Oct 22, 2025

An AI-driven model accurately detects imaging-based extranodal extension in HPV-positive oropharyngeal cancer from CT scans, improving outcome prediction beyond expert radiologist assessments and identifying patients at higher risk of poore

Advancing Early Pediatric Sepsis Detection: Machine Learning Models Predicting Onset Within 48 Hours
AIemergency medicinemachine learning

Advancing Early Pediatric Sepsis Detection: Machine Learning Models Predicting Onset Within 48 Hours

By MedXY|Oct 21, 2025

This study developed and validated machine learning models with high accuracy to predict early pediatric sepsis and septic shock within 48 hours using multisite electronic health record data in emergency departments.

Medicare Advantage and Cancer Surgery Outcomes: Are Patients Being Routed Away from High-Quality Hospitals?
AIhealth disparitiesMedicare Advantage

Medicare Advantage and Cancer Surgery Outcomes: Are Patients Being Routed Away from High-Quality Hospitals?

By MedXY|Oct 21, 2025

This retrospective national cohort study reveals that Medicare Advantage (MA) enrollees undergoing major cancer surgery are less likely to receive care at high-quality hospitals compared to traditional Medicare beneficiaries, raising concer

Enhancing Melanoma Prognosis: AI-Driven Quantification of Tumor-Infiltrating Lymphocytes Outperforms Traditional Pathology
AIartificial intelligencemelanoma

Enhancing Melanoma Prognosis: AI-Driven Quantification of Tumor-Infiltrating Lymphocytes Outperforms Traditional Pathology

By MedXY|Oct 21, 2025

This study demonstrates that an AI algorithm provides more reproducible and prognostically relevant assessment of tumor-infiltrating lymphocytes in melanoma compared to traditional pathologist methods, offering a promising tool to improve c

Artificial Intelligence-Detected Tumor-Infiltrating Lymphocytes as a Biomarker in Anti-PD-1-Based Therapy for Advanced Melanoma: Clinical Evidence and Translational Perspectives
AIartificial intelligenceimmune checkpoint inhibitors

Artificial Intelligence-Detected Tumor-Infiltrating Lymphocytes as a Biomarker in Anti-PD-1-Based Therapy for Advanced Melanoma: Clinical Evidence and Translational Perspectives

By MedXY|Oct 21, 2025

AI-detected tumor-infiltrating lymphocytes on routine histology independently predict response and survival in advanced melanoma treated with anti-PD-1 therapies, outperforming manual scoring and offering an accessible biomarker for immune

患者向けデジタルヘルス介入による肺がんスクリーニング受診率の向上:ランダム化比較試験からの洞察
AI

患者向けデジタルヘルス介入による肺がんスクリーニング受診率の向上:ランダム化比較試験からの洞察

By MedXY|Oct 21, 2025

デジタルヘルスプログラムは、高リスク個体の肺がんスクリーニング率を大幅に向上させ、予防医療の改善にデジタルツールの潜在力を示しています。

Enhancing Lung Cancer Screening Uptake Through a Direct-to-Patient Digital Health Intervention: Insights from a Randomized Clinical Trial
AIrandomized clinical trial

Enhancing Lung Cancer Screening Uptake Through a Direct-to-Patient Digital Health Intervention: Insights from a Randomized Clinical Trial

By MedXY|Oct 21, 2025

A digital health program significantly increased lung cancer screening rates among high-risk individuals, underscoring digital tools’ potential to improve preventive care.

Navigating the AI Revolution in Health Care: Insights from the JAMA Summit
AIartificial intelligenceEquity

Navigating the AI Revolution in Health Care: Insights from the JAMA Summit

By MedXY|Oct 14, 2025

Artificial intelligence is reshaping health care, offering vast potential benefits alongside significant challenges. The JAMA Summit emphasizes the need for robust evaluation, equitable deployment, and multi-stakeholder collaboration to ens

Harnessing Artificial Intelligence for Diagnosing Sexually Transmitted Infections and Anogenital Dermatoses: Insights from a Systematic Review and Meta-Analysis
AIartificial intelligenceSexually Transmitted Infections

Harnessing Artificial Intelligence for Diagnosing Sexually Transmitted Infections and Anogenital Dermatoses: Insights from a Systematic Review and Meta-Analysis

By MedXY|Oct 6, 2025

AI demonstrates high accuracy in identifying mpox and other anogenital conditions from clinical images, yet significant research gaps and validation needs remain before clinical adoption.

Decoding Nonverbal Learning Disability in Children: Distinct Profiles and Their Clinical Implications
AI

Decoding Nonverbal Learning Disability in Children: Distinct Profiles and Their Clinical Implications

By MedXY|Oct 6, 2025

A cross-sectional study identifies four distinct profiles of nonverbal learning disability (NVLD) in children, revealing significant heterogeneity in visual-spatial deficits, academic skills, and psychiatric diagnoses, highlighting implicat

Evaluating Medical Education Microvideos on TikTok: Quality Versus Popularity in Latin America
AIMedical EducationTikTok

Evaluating Medical Education Microvideos on TikTok: Quality Versus Popularity in Latin America

By MedXY|Oct 6, 2025

This study assesses the educational quality and popularity of Spanish-language medical microvideos on TikTok in Latin America, revealing a discordance between engagement metrics and content quality, emphasizing the need for integrated evalu

Evaluating Anemia-Related YouTube Videos: Reliable Education or Misinformation Risk?
AIanemia

Evaluating Anemia-Related YouTube Videos: Reliable Education or Misinformation Risk?

By MedXY|Oct 6, 2025

A recent study assessed the quality, reliability, and popularity of anemia-related videos on YouTube, revealing moderate variability and highlighting the importance of health professionals’ involvement to ensure accurate online conten

Evaluating the Clinical Generalizability of FDA-Approved AI-Enabled Medical Devices: Insights and Implications
AIFDA approval

Evaluating the Clinical Generalizability of FDA-Approved AI-Enabled Medical Devices: Insights and Implications

By MedXY|Oct 6, 2025

A comprehensive analysis of 903 FDA-approved AI medical devices reveals limited clinical performance data and demographic inclusivity, underscoring the need for ongoing evaluation to ensure safe, effective clinical application.

Advancing Precision Medicine in Hepatocellular Carcinoma: Machine Learning Radiomic Models Surpass Clinical Biomarkers in Predicting Immunotherapy Outcomes
AIhepatocellular carcinomaimmunotherapy

Advancing Precision Medicine in Hepatocellular Carcinoma: Machine Learning Radiomic Models Surpass Clinical Biomarkers in Predicting Immunotherapy Outcomes

By MedXY|Oct 9, 2025

Integrated radiomic-clinical machine learning models outperform traditional clinical biomarkers in predicting survival and treatment response in unresectable hepatocellular carcinoma patients undergoing atezolizumab plus bevacizumab therapy

Harnessing Artificial Intelligence for Enhanced Prediction of Complete Heart Block Risk via Electrocardiography
AIartificial intelligenceElectrocardiography

Harnessing Artificial Intelligence for Enhanced Prediction of Complete Heart Block Risk via Electrocardiography

By MedXY|Oct 9, 2025

AIRE-CHB, a novel AI-enhanced ECG model, significantly improves prediction of incident complete heart block, outperforming traditional bifascicular block assessment and offering promising clinical utility in risk stratification and manageme

Enhancing Fibrosis Scoring in MASH: The Role of AI-Enhanced Digital Pathology
AIclinical trialsfibrosis

Enhancing Fibrosis Scoring in MASH: The Role of AI-Enhanced Digital Pathology

By MedXY|Oct 8, 2025

AI-assisted digital pathology improves inter-pathologist agreement on fibrosis staging in metabolic dysfunction-associated steatohepatitis (MASH), enhancing clinical trial accuracy and efficiency.

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