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GastroenterologyDREAM techniqueHội chứng ruột ngắn

Innovative DREAM Technique Restores Intestinal and Hepatic Function in Short Bowel Syndrome

By MedXY|Jul 1, 2026

The DREAM method enables complete enteral nutrition in short bowel syndrome, enhancing intestinal adaptation and protecting liver function by restoring gut-liver signaling pathways, as demonstrated in a neonatal pig model.

Clinical UpdatesHepatoprotectionHội chứng ruột ngắn

Targeted Gut-Liver Axis Modulation: The Therapeutic Potential of Gut-Restricted LXR Agonists in Short Bowel Syndrome

By MedXY|Mar 11, 2026

This review explores the development of WUSTL0717, a gut-restricted LXR agonist that mitigates liver injury in short bowel syndrome by leveraging the intestinal HDL-ApoA1 pathway without inducing systemic metabolic complications.