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MAIPI: A Novel AI-Powered Prognostic Index for Mantle Cell Lymphoma Using Routine Histology
AIartificial intelligencedeep learning

MAIPI: A Novel AI-Powered Prognostic Index for Mantle Cell Lymphoma Using Routine Histology

By MedXY|Jul 12, 2026

The MAIPI deep learning model offers a novel, accurate prognosis tool for mantle cell lymphoma, using standard H&E stained biopsy images, bypassing need for molecular tests or expert pathology, and enhancing risk stratification for indi

Fixed‑Duration Venetoclax After RBAC Improves 2‑Year PFS in High‑Risk Older Mantle Cell Lymphoma: Final Results of the FIL_V‑RBAC Phase 2 Study
Hematology-OncologyMantle Cell Lymphomavenetoclax

Fixed‑Duration Venetoclax After RBAC Improves 2‑Year PFS in High‑Risk Older Mantle Cell Lymphoma: Final Results of the FIL_V‑RBAC Phase 2 Study

By MedXY|Nov 25, 2025

In a multicentre, risk‑adapted phase 2 trial, adding fixed‑duration venetoclax after rituximab‑bendamustine‑cytarabine (RBAC) produced a 2‑year progression‑free survival of 60% in older patients with high‑risk mantle cell lymphoma (MCL). To

Ibrutinib-Rituximab versus Immunochemotherapy: A Paradigm Shift in First-Line Treatment for Older Mantle Cell Lymphoma Patients
Hematology-OncologyIbrutinibImmunochemotherapy

Ibrutinib-Rituximab versus Immunochemotherapy: A Paradigm Shift in First-Line Treatment for Older Mantle Cell Lymphoma Patients

By MedXY|Oct 10, 2025

The ENRICH trial demonstrates that ibrutinib combined with rituximab significantly improves progression-free survival compared to standard immunochemotherapy in older patients with untreated mantle cell lymphoma, heralding a new chemotherap

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