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Unraveling Fibroblast Diversity in Vaginal Wall Prolapse: Insights from Single-Nucleus Transcriptomics
newsMa trận ngoại tế bàoSingle-nucleus RNA sequencing

Unraveling Fibroblast Diversity in Vaginal Wall Prolapse: Insights from Single-Nucleus Transcriptomics

By MedXY|Aug 18, 2026

This study reveals distinct fibroblast subpopulations in pelvic organ prolapse tissue, showing a shift toward pro-inflammatory and matrix-degrading phenotypes that impair extracellular matrix integrity and tissue repair.

Molecular Profiling of Benign Vocal Fold Lesions: Differential Gene Expression in Polyps versus Reinke’s Edema
Clinical Updatesgene expressionMa trận ngoại tế bào
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Molecular Profiling of Benign Vocal Fold Lesions: Differential Gene Expression in Polyps versus Reinke’s Edema

By MedXY|Mar 18, 2026

This review explores the transcriptomic distinctions between vocal fold polyps and Reinke’s edema, focusing on the upregulation of COL1A1, FN1, and MMP-9 in polyps as key diagnostic and mechanistic markers.

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