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MedXY AI/MedXY News/Tag: Congenital Malformations
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Lithium Use in Pregnancy: Balancing Risks of Spontaneous Preterm Birth, Cardiac Malformations, and Fetal Growth
newsCongenital MalformationsPregnancy

Lithium Use in Pregnancy: Balancing Risks of Spontaneous Preterm Birth, Cardiac Malformations, and Fetal Growth

By MedXY|Aug 18, 2026

A statewide Australian cohort study reveals lithium exposure during pregnancy doubles risk of spontaneous preterm birth and raises risks of cardiac malformations and large-for-gestational-age infants, informing clinical decision-making.

First-Trimester Z-Drug Exposure Does Not Increase Overall Risk of Congenital Malformations
newsCongenital MalformationsPregnancy

First-Trimester Z-Drug Exposure Does Not Increase Overall Risk of Congenital Malformations

By MedXY|Dec 23, 2025

A large-scale US cohort study of over 4.2 million pregnancies found no significant association between first-trimester Z-drug exposure—primarily zolpidem—and major congenital malformations, providing clinical reassurance for managing severe

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