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Polygenic Influences and Anticholinergic Burden: Unraveling Their Joint Impact on Cognition and Brain Structure in Psychosis Spectrum Disorders
Neurologybrain structurecognition

Polygenic Influences and Anticholinergic Burden: Unraveling Their Joint Impact on Cognition and Brain Structure in Psychosis Spectrum Disorders

By MedXY|Oct 30, 2025

This study reveals that genetic predispositions interact with anticholinergic medication burden to influence cognitive deficits and brain gray matter volume reductions in psychosis spectrum disorders, offering new insights into personalized

Life Course Air Pollution Exposure and Cognitive Decline: Insights from the 1946 British Birth Cohort
Neurologyagingair pollution
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Life Course Air Pollution Exposure and Cognitive Decline: Insights from the 1946 British Birth Cohort

By MedXY|Oct 20, 2025

This population-based study reveals that midlife exposure to nitrogen dioxide and particulate matter correlates with poorer cognitive function and adverse brain structural changes in later life, underscoring the neurocognitive risks of air

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