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More Than Half of Hispanic Medicare Beneficiaries Aged 65+ Have Hearing Loss — Yet Few Use Hearing Aids
newshearing aidspublic health

More Than Half of Hispanic Medicare Beneficiaries Aged 65+ Have Hearing Loss — Yet Few Use Hearing Aids

By MedXY|Nov 25, 2025

A nationally representative 2022 study found hearing loss in 54.6% of Hispanic US adults 65+; only 8.3% of those with hearing loss reported using hearing aids, underscoring major access gaps.

Invisible Invaders: How Microplastics May Accelerate Atherosclerosis — and Why Men Could Be at Greater Risk
Cardiologyatherosclerosiscardiovascular risk

Invisible Invaders: How Microplastics May Accelerate Atherosclerosis — and Why Men Could Be at Greater Risk

By MedXY|Nov 25, 2025

New animal research links oral microplastic exposure to dramatic increases in arterial plaque—especially in males—by injuring endothelial cells and provoking inflammation and oxidative stress.

Geographic Clusters of Late-Life Epilepsy in US Medicare: Sleep and Mobility as Key Contextual Drivers
Neurologyepilepsyolder adults

Geographic Clusters of Late-Life Epilepsy in US Medicare: Sleep and Mobility as Key Contextual Drivers

By MedXY|Nov 25, 2025

A Medicare cohort study mapped incident epilepsy among older adults across the contiguous US and linked high-incidence areas to social and environmental determinants—most strongly insufficient sleep and lack of household vehicle access—sugg

Rising Inhaler Emissions in the US: 1.6 Billion Devices, 25 Million Tons CO2e, and $5.7B in Social Costs
newsclimate change

Rising Inhaler Emissions in the US: 1.6 Billion Devices, 25 Million Tons CO2e, and $5.7B in Social Costs

By MedXY|Nov 25, 2025

A JAMA serial cross‑sectional analysis finds US outpatient inhaler dispensing (2014–2024) produced ~24.9 million metric tons CO2e, mostly from metered‑dose inhalers; policy and clinical shifts to dry‑powder/soft‑mist devices and low‑GWP pro

High, Persistent Breast Cancer Mortality in Sub‑Saharan Africa: 7‑Year ABC‑DO Cohort Reveals Major Survival Gaps and Actionable Targets
newsbreast cancerSub-Saharan Africa

High, Persistent Breast Cancer Mortality in Sub‑Saharan Africa: 7‑Year ABC‑DO Cohort Reveals Major Survival Gaps and Actionable Targets

By MedXY|Nov 25, 2025

A 7‑year follow-up of 2,153 women in the ABC‑DO cohort shows poor breast cancer survival in much of sub‑Saharan Africa, with 5‑year crude survival 40% and marked between-country and racial disparities; reaching WHO stage downstaging targets

Most Adolescents and Young Adults with Solid Tumours Reach Near-Normal 5-Year Survival Within Four Years — Implications for ‘Right to be Forgotten’ Policies
newssurvivorship

Most Adolescents and Young Adults with Solid Tumours Reach Near-Normal 5-Year Survival Within Four Years — Implications for ‘Right to be Forgotten’ Policies

By MedXY|Nov 24, 2025

Population-based Dutch data show that AYA survivors of most solid malignancies achieve five-year conditional relative survival >95% by four years post-diagnosis, supporting reconsideration of blanket 10‑year disclosure periods in Right t

Immunogenicity and HPV Infection After One, Two, and Three Doses of Quadrivalent HPV Vaccine in Indian Girls: A Multicentre Prospective Cohort Study
Infectious Diseasescervical cancer preventionHPV vaccine

Immunogenicity and HPV Infection After One, Two, and Three Doses of Quadrivalent HPV Vaccine in Indian Girls: A Multicentre Prospective Cohort Study

By MedXY|Nov 24, 2025

This study evaluates immune responses and HPV infection rates in Indian girls after receiving one, two, or three doses of the quadrivalent HPV vaccine, supporting WHO’s recommendation for two doses spaced at least six months apart.

Single-dose Cervarix induces durable seropositivity but fails HPV‑16 GMC non-inferiority versus three-dose Gardasil-4: implications from the PRIMAVERA immunobridging trial
Infectious DiseasesHPV vaccineimmunobridging

Single-dose Cervarix induces durable seropositivity but fails HPV‑16 GMC non-inferiority versus three-dose Gardasil-4: implications from the PRIMAVERA immunobridging trial

By MedXY|Nov 24, 2025

PRIMAVERA immunobridging shows single-dose Cervarix induces near-universal seropositivity at 36 months and non-inferior HPV-18 antibodies versus three-dose Gardasil-4, but HPV-16 antibody GMCs were lower; results inform but do not yet suppo

Rare but Real: Higher Risks of Vascular and Inflammatory Disease After SARS‑CoV‑2 Infection Than After BNT162b2 Vaccination in Children and Adolescents
newsCOVID-19 vaccinationmyocarditis

Rare but Real: Higher Risks of Vascular and Inflammatory Disease After SARS‑CoV‑2 Infection Than After BNT162b2 Vaccination in Children and Adolescents

By MedXY|Nov 24, 2025

A nationwide English cohort study (n≈13.9M) found transient but significant increases in rare vascular and inflammatory events after first SARS‑CoV‑2 infection and a smaller, short-lived increase in myocarditis/pericarditis after first BNT1

Human Monoclonal Antibody MAM01 for Malaria Prevention: Phase 1 Trial Insights and Context in Antimalarial Monoclonal Antibody Development
Clinical Updatesclinical trialmalaria

Human Monoclonal Antibody MAM01 for Malaria Prevention: Phase 1 Trial Insights and Context in Antimalarial Monoclonal Antibody Development

By MedXY|Nov 23, 2025

This review synthesizes evidence on MAM01, a monoclonal antibody targeting Plasmodium falciparum circumsporozoite protein, summarizing its first-in-human phase 1 trial demonstrating safety and protective efficacy, alongside contextual advan

A Standard Set for Healthy Aging in Primary Care: Key Recommendations from the New Core Outcome Set (COS) Consensus
Family Medicine & Nutritionhealthy agingprimary care

A Standard Set for Healthy Aging in Primary Care: Key Recommendations from the New Core Outcome Set (COS) Consensus

By MedXY|Nov 23, 2025

A concise overview of the newly developed Core Outcome Set for healthy aging in primary care—12 prioritized outcomes to standardize evaluation of health-promotion interventions and improve comparability across studies and programs.

What, When and How to Measure Post COVID-19 Condition: The New Core Outcome Set for Clinical Trials
newsclinical trialslong COVID

What, When and How to Measure Post COVID-19 Condition: The New Core Outcome Set for Clinical Trials

By MedXY|Nov 23, 2025

A concise guide to the newly published Core Outcome Set for Post COVID-19 Condition (COS‑PCC): the nine prioritized outcomes, recommended measurement instruments, timing considerations, and implications for research and care.

DEN-CORE: An international consensus COMS to standardise dengue clinical trials
Infectious Diseasesclinical trialsDengue

DEN-CORE: An international consensus COMS to standardise dengue clinical trials

By MedXY|Nov 23, 2025

An international Delphi consensus defined a Core Outcome Measurement Set (COMS) for dengue trials to harmonise outcome selection and measurement across settings, improving comparability and evidence synthesis.

Marburg Virus Disease in Rwanda, 2024: Epidemiology, Clinical Management, and Public Health Response
Clinical Updates

Marburg Virus Disease in Rwanda, 2024: Epidemiology, Clinical Management, and Public Health Response

By MedXY|Nov 23, 2025

This review synthesizes evidence from Rwanda’s 2024 Marburg virus disease outbreak, highlighting epidemiologic characteristics, clinical presentations, investigational therapeutics, and vaccine deployment strategies that contributed t

Long-Term Clinical and Immunological Landscape Following Monkeypox Virus Infection and MVA-BN Vaccination: Insights from the Belgian MPX-COHORT and POQS-FU-PLUS Studies
Clinical UpdatesMVA-BNワクチン

Long-Term Clinical and Immunological Landscape Following Monkeypox Virus Infection and MVA-BN Vaccination: Insights from the Belgian MPX-COHORT and POQS-FU-PLUS Studies

By MedXY|Nov 23, 2025

This review synthesizes 24-month follow-up data on monkeypox virus infection and MVA-BN vaccination, detailing durable immunity post-infection, comparative antibody kinetics, and clinical sequelae, informing future vaccination strategies an

A Single Shot Against Rift Valley Fever? Phase 1 ChAdOx1 RVF Trial Shows Acceptable Safety and Robust Immune Responses in Uganda
Infectious DiseasesimmunogenicityVaccine

A Single Shot Against Rift Valley Fever? Phase 1 ChAdOx1 RVF Trial Shows Acceptable Safety and Robust Immune Responses in Uganda

By MedXY|Nov 23, 2025

In a randomized, placebo-controlled phase 1 trial in Uganda, a single intramuscular dose of ChAdOx1 RVF (adenovirus-vectored) was well tolerated and induced rapid T-cell responses and neutralising antibodies, supporting further evaluation o

Targeted Vaccination Is Most Efficient but Not Cost‑Effective: National Serosurvey and Modelling of Japanese Encephalitis in Bangladesh
Infectious Diseasesvaccine policy

Targeted Vaccination Is Most Efficient but Not Cost‑Effective: National Serosurvey and Modelling of Japanese Encephalitis in Bangladesh

By MedXY|Nov 23, 2025

A nationally representative serosurvey and transmission modelling study in Bangladesh estimates low population-level JEV exposure but large numbers of infections annually; spatially targeted vaccination would be most efficient, though not c

Post‑COVID Resurgence of Mycoplasma pneumoniae in French Children: Hospital Burden, Risk Factors for ICU Admission, and Clinical Implications
Critical CareMycoplasma pneumoniaePediatrics

Post‑COVID Resurgence of Mycoplasma pneumoniae in French Children: Hospital Burden, Risk Factors for ICU Admission, and Clinical Implications

By MedXY|Nov 23, 2025

A nationwide French multicentre cohort (ORIGAMI) documents a substantial 2023–24 paediatric hospitalisation surge from Mycoplasma pneumoniae, identifies older age, asthma, comorbidity and erythema multiforme as ICU risk factors, and highlig

Brand-Specific Influenza Vaccine Effectiveness in Nordic Older Adults: Insights from the 2024-2025 Season Registry-Based Target Trial Emulation
Clinical Updatesinfluenza vaccineolder adults

Brand-Specific Influenza Vaccine Effectiveness in Nordic Older Adults: Insights from the 2024-2025 Season Registry-Based Target Trial Emulation

By MedXY|Nov 23, 2025

This comprehensive review synthesizes recent evidence on brand-specific influenza vaccine effectiveness (VE) among adults aged ≥65 in Denmark, Finland, and Sweden during the 2024-2025 season, underscoring heterogeneous VE profiles and the c

Peer Self-harm Predicts a Small Increase in Adolescent Risk with a Peak at Age 16: Findings from a Nationwide Finnish Cohort
newsadolescentsself-harm

Peer Self-harm Predicts a Small Increase in Adolescent Risk with a Peak at Age 16: Findings from a Nationwide Finnish Cohort

By MedXY|Nov 23, 2025

A Finnish registry cohort (n=913,149) found that exposure to same-grade schoolmates’ self-harm modestly increased later self-harm risk (HR 1.05), with the largest effect around age 16 (HR ~1.45), suggesting time-limited social transmi

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