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This population-based study reveals that midlife exposure to nitrogen dioxide and particulate matter correlates with poorer cognitive function and adverse brain structural changes in later life, underscoring the neurocognitive risks of air
The G-oncoCOACH trial demonstrates that comprehensive geriatric assessment combined with geriatric team implementation and extensive patient coaching significantly improves quality of life in older patients with solid tumors undergoing syst
A large-scale analysis reveals high frailty prevalence among people experiencing homelessness in England, highlighting critical socioeconomic factors influencing vulnerability.
A cluster randomised controlled trial demonstrates that the Conversations about Suicide course delivered in Australian Men’s Sheds significantly improves recommended suicide prevention actions among older men, with sustained effects a
A large randomized controlled trial found that an Iyengar yoga-based exercise program increased fall rates among older adults compared to seated relaxation yoga, despite improvements in physical activity and balance confidence, highlighting
A large-scale network meta-analysis highlights that combined physical exercise and cognitive training most effectively improve cognition in older adults without impairment, emphasizing tailored lifestyle strategies for dementia prevention.
Smoking cessation in middle-aged and older adults is linked to a slower decline in memory and fluency over six years, suggesting quitting smoking benefits long-term cognitive health regardless of age at cessation.
A UK cohort study reveals that adolescent dysmenorrhoea increases the risk of chronic pain in adulthood, highlighting the need for early identification and management.
This systematic analysis of the GBD 2023 presents global trends in disease burden, risk factors, and healthy life expectancy across 204 countries, elucidating shifts in NCDs, CMNN diseases, injuries, and underlying risk drivers crucial for
A comprehensive analysis reveals ongoing challenges in diabetes diagnosis, treatment, and glycaemic control worldwide, highlighting the urgent need for enhanced care strategies, especially in low- and middle-income regions.
This study highlights how poor mental well-being during adolescence predicts increased risks of mental illness, risky behaviors, and mortality in young adulthood, emphasizing the urgency for early identification and intervention.
A nationwide study in Spain from 2018 to 2023 reveals increasing rates of non-lethal intentional self-harm and suicide, particularly among young women, underscoring the need for targeted mental health interventions.
Stimulant use disorder diagnoses in young adult Medicaid enrollees have markedly increased from 2001 to 2020, especially for noncocaine psychostimulants, highlighting an urgent need for targeted interventions and evidence-based treatments a
This systematic review and meta-analysis demonstrates that flavan-3-ol-rich foods significantly lower blood pressure and improve endothelial function, supporting their role in cardiovascular prevention, especially in individuals with elevat
This meta-analysis examines dropout rates in digital psychosocial interventions for adult illicit drug users, identifying key demographic, clinical, and intervention-related factors associated with treatment adherence.
Nurse-led interventions, especially intensive counseling combined with varenicline or family-based approaches, significantly enhance smoking cessation rates. Brief advice and counseling also improve outcomes over usual care, supporting nurs
The ARON trial demonstrated that a clinical decision tool combining decision tree, point-of-care CRP testing, and safety-netting advice safely reduces antibiotic prescribing in acutely ill children without delaying recovery or increasing he
Recent advances in anti-β amyloid monoclonal antibodies offer promising reductions in Alzheimer’s disease progression but spark debate regarding their clinical impact, cost-effectiveness, and accessibility. Emerging biomarkers and preventiv
One in five UK patients with Rome IV IBS regularly use opioids, associated with worse quality of life, more psychological distress, and increased healthcare costs, highlighting a critical need for opioid stewardship in IBS management.
Early-onset breast cancer incidence in France has steadily increased over the past three decades, mirroring trends in other Western countries. Shifts in hormonal and lifestyle factors may contribute, highlighting the need for adapted preven
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