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Patients with hidradenitis suppurativa face a significantly increased risk of new-onset depression and anxiety, independent of disease severity, highlighting the need for universal psychiatric assessment in this population.
A large Dutch cohort study reveals that substituting TV-watching time with physical activities or sleep significantly lowers major depression risk, especially in middle-aged adults, highlighting the mental health benefits of an active lifes
Novel benzodiazepine coexposure in opioid overdoses significantly increases the risk of mechanical ventilation and naloxone nonresponse, highlighting a critical challenge in emergency care management.
Pharmaceutical companies have significantly increased marketing payments to clinicians for ADHD medications, particularly targeting advanced practice clinicians. The impact of this trend on prescribing patterns and clinical benefits remains
Discover nine brain- and body-friendly foods that improve mood, reduce inflammation, stabilize blood sugar, and offer potential cancer-protective benefits, supporting both emotional well-being and long-term health.
A prospective study reveals that nearly 20% of surgical patients experience postoperative delirium in the PACU, with elevated preoperative anxiety significantly increasing this risk. Implementation of a brain health care bundle improves man
This article explores how gastrointestinal diseases are linked to sleep disturbances, highlighting depression as a partial mediator and emphasizing the importance of addressing both gut and psychological health to improve sleep quality.
Mental disorders currently diagnosed symptomatically can be redefined using biology-informed frameworks integrating biological, behavioral, and environmental data. The Precision Psychiatry Roadmap aims to harmonize global research and clini
Recent evidence reveals gut dysbiosis-induced vitamin B6 metabolic disturbances as a novel, cortisol-independent mechanism driving chronic stress-related abnormal behaviors and inflammation, highlighting probiotic and vitamin B6 supplementa
This analysis reveals that varenicline is the most effective and safe pharmacotherapy for smoking cessation in individuals with current or past major depressive disorder, outperforming bupropion and nicotine patches with no increased neurop
A randomized trial assessing AI-generated study materials revealed no significant impact on pharmacy students’ objective structured clinical examination scores or test anxiety levels, highlighting the need for further research on long-term
A 16-week randomized trial demonstrates that AI chatbots with high-social-cue design significantly reduce depression and anxiety symptoms in college students compared to text-only chatbots, improving adherence, satisfaction, and therapeutic
Closed-loop auditory exposure during slow-wave sleep significantly reduces craving and playtime in Internet Gaming Disorder by modulating sleep spindle power, offering a novel, non-invasive therapeutic strategy.
This RCT demonstrates that disposable e-cigarettes significantly reduce carcinogen levels short-term among smokers with serious mental illness, underscoring the need for behavioral support to sustain harm reduction.
This review synthesizes evidence from a randomized trial and real-world studies showing esketamine’s efficacy and safety in smoking cessation among lung cancer patients with MDD, as well as in treatment-resistant depression, highlight
Longitudinal observational data reveal that as adolescents increase cigarette use, their immediate post-smoking mood stabilizes, with boys showing stabilization in background mood as well.
This RCT assessed a proactive e-health intervention for patients with at-risk alcohol use and depressive symptoms, showing high adherence but only small, non-significant improvements at 12 months and no lasting effects at 24 months.
This study reveals an increased risk of infections among schizophrenia patients treated with clozapine compared to olanzapine, highlighting the need for vigilant infection monitoring and preventive care.
A survey reveals significant increases in depression and anxiety rates among various racial groups during the COVID-19 pandemic, highlighting ongoing racial health disparities.
This review synthesizes evidence from a multicenter RCT showing ALM-003 digital therapeutic reduces heavy drinking days significantly in alcohol-dependent individuals at high risk, with an excellent safety profile.
