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New GRADE sub-study reveals that somatic symptoms of depression, not cognitive-affective symptoms, are chiefly associated with inflammation and insulin resistance in type 2 diabetes, highlighting a pathophysiological bridge for targeted int
Weekly LYN-005 demonstrated pharmacokinetic equivalence to daily risperidone, sustained therapeutic levels, and manageable safety in clinically stable patients, offering a novel option to address non-adherence in schizophrenia.
Semaglutide significantly reduced body weight without impacting psychotic symptoms or clozapine levels in people with schizophrenia and obesity on clozapine therapy.
Recent trials show no significant difference in smoking cessation rates between e-cigarettes and combination nicotine replacement therapy among patients discharged from inpatient substance use withdrawal services. Longitudinal analyses reve
Two randomized controlled trials evaluated immersive VR therapies targeting auditory verbal hallucinations and persecutory delusions in schizophrenia and psychosis, revealing modest benefits for hallucinations but no superior effect for cog
A UK multicentre, double-blind, placebo-controlled trial demonstrates that pramipexole augmentation at 2.5 mg reduces depressive symptoms in treatment-resistant unipolar depression at 12 weeks, with some adverse effects noted, supporting it
A large national study shows opioid prescribing for ED low back pain fell sharply from 2016 to 2022, while radiograph use remained high and unchanged.
Massachusetts General Hospital leads the 2025-2026 US News psychiatric hospital rankings. Rankings highlight excellence in psychiatric care, but methodological nuances and clinical implications warrant closer examination.
Overdose deaths from synthetic opioids alone in U.S. youth aged 15–24 surged 168% between 2018 and 2022, now representing one-third of all youth OD fatalities. Clinical vigilance, harm reduction, and targeted prevention are urgently needed.
A recent survey found 39% of elective sports surgery patients used CBD for pain or sleep, with one-third reporting benefit—underscoring the need for more evidence and opioid alternatives.
An FDA expert panel debates the risks and benefits of SSRI antidepressants in pregnancy, emphasizing the need to weigh untreated depression risks against potential drug-related fetal outcomes.
Maternal depression significantly affects the quality of parenting, impairing mother-child bonding and other key behaviors. This article explores recent research, implications, and interventions.
A new study highlights the psychosocial factors contributing to depression in women with premature ovarian insufficiency, emphasizing the need for holistic care.
Vaginismus, an involuntary contraction of vaginal muscles, affects intimacy and health. We explore its causes, health impact, and evidence-based treatment strategies.
Discover how thoughts, emotions, and beliefs can profoundly shape health, exploring scientific evidence, common misconceptions, and practical strategies to optimize the mind-body connection.
Exploring the unique challenges of adolescent brain development, this article unpacks the science, dispels myths, and offers practical strategies for supporting teen mental health.
Online interactions have revolutionized the way we communicate, learn, and connect with one another. Yet,...