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A clear, clinician-focused summary of the 2025 VA/DoD guideline update: new screening thresholds, streamlined treatment pathways, integration of pharmacotherapy (including GLP‑1 receptor agonists), endoscopic and surgical options, and veter
Following the 2018 MISSION Act expansion, VA specialty referrals and community care outsourcing increased substantially without reducing outpatient specialty wait times, signaling the need for alternative access-improvement strategies.
This study identifies baseline frailty, organ dysfunction severity, and corticosteroid use as independent predictors of severe post-intensive care frailty in older septic shock survivors, highlighting critical factors for targeted post-ICU
This study found that patient-physician sex concordance does not influence diagnostic accuracy in primary care, but female physicians consistently outperform male counterparts in diagnosing complex conditions such as POTS and syphilis, high
This study highlights that geriatric vulnerabilities and comorbidities, once considered nonmodifiable, play a dominant role in 30-day readmissions after colorectal surgery in older adults, emphasizing the need for integrated perioperative i
Randomized Quality Improvement (RQI) trials offer robust evidence for healthcare interventions but raise ethical and regulatory challenges. A proposed framework provides streamlined oversight enabling safer, evidence-based care improvements
This qualitative study reveals that patients undergoing pulmonary function tests face emotional and informational challenges. A co-developed educational pamphlet improves understanding and may reduce anxiety, highlighting the need for patie
Histidine-rich glycoprotein (HRG) directly modulates platelet adhesion and aggregation by binding platelet receptors GPIbα and GPIIb/IIIa, competing with key ligands VWF and fibrinogen, thus attenuating thrombus formation; reduced HRG in se
Bempedoic acid reduces the risk of major adverse limb and cardiovascular events in statin-intolerant patients with peripheral artery disease, illustrating its potential to enhance vascular risk management.
This study highlights how unmet transportation needs significantly increase missed in-person primary care appointments, while telemedicine offers a viable solution to overcome these barriers, improving healthcare access.
Changes in NT-proBNP levels over three years define heart stress status, which improves cardiovascular and mortality risk prediction in older adults without prior CVD, underscoring its utility in clinical risk stratification.
This study evaluates how ICU room characteristics, including room type and visibility, influence mortality and length of stay, finding single rooms increase length of stay without affecting mortality.
This study reveals that copeptin kinetics remain mostly intact in healthy aging, but older adults exhibit diminished copeptin suppression after hydration, potentially explaining their increased vulnerability to hyponatremia.
This article explores primary care providers’ perspectives on real-time benefit tools (RTBTs) embedded in electronic health records, highlighting their potential for cost-conscious prescribing amidst challenges like incomplete data an
Experience-based continuous glucose monitoring (CGM) curricula significantly improve internal medicine residents’ confidence in applied patient care skills compared to traditional approaches, supporting hands-on CGM training integrati
Cryptogenic steatotic liver disease (SLD) is a form of fatty liver disease found in lean individuals without diabetes or other metabolic risk factors, associated with significant liver injury and increased mortality risk.
The STATICH trial assessed safety and efficacy of antiplatelet therapy after intracerebral hemorrhage, revealing increased hemorrhagic risk but fewer ischemic events among treated patients, highlighting ongoing clinical dilemmas.
This study emulated a target trial to compare ultra-early (0-3h) versus early (>3-6h) vasopressin initiation after norepinephrine escalation in septic shock, revealing significant mortality and renal therapy benefits with ultra-early use
A novel longitudinal obesity medicine training pathway for internal medicine residents, implemented at an urban Federally Qualified Health Center, improves physician confidence and management skills in obesity care, preparing trainees for b
A national survey reveals that general internal medicine research fellowships are vital for developing research skills and careers but face challenges including training gaps and recruitment difficulties.
Open language-specific specialty feeds and department pages.