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MVA-BN vaccination is safe and effective against mpox in at-risk populations, but reduced protection is noted in people living with HIV. Dose strategies and patient immunological status may affect outcomes.
A Danish multicentre trial found individualised, shorter antibiotic regimens for febrile pediatric UTIs reduce overall antibiotic exposure and adverse events, but with a modestly higher recurrence risk compared to standard 10-day treatment.
A Cambodian study shows that a 14-day high-dose primaquine regimen (7.0 mg/kg) significantly reduces Plasmodium vivax relapse compared to the standard low-dose (3.5 mg/kg), with comparable safety in G6PD-normal patients.
A multicountry outbreak of diphtheria among migrants in Europe raised concerns about cutaneous and respiratory disease, cross-border spread, and emerging antibiotic resistance. Genomic analysis revealed multiclonal transmission and resistan
Recent cluster-randomized trials in Kenya and Burkina Faso provide mixed but informative evidence on the efficacy and safety of mass ivermectin administration for malaria control, highlighting both its potential and limitations.
FMT is noninferior to vancomycin for primary CDI, with similar cure rates and safety, suggesting it may be a viable first-line therapy.
West Nile virus is the leading mosquito-borne disease in the U.S., causing significant neuroinvasive morbidity and mortality, especially in older and immunocompromised individuals. With no approved treatments or vaccines, prevention and sur
Blocking both IL-17A and IL-17F impairs neutrophil migration, reducing antifungal defense and raising candidiasis risk in patients on bimekizumab, according to in vitro evidence.
Norovirus vaccines show promise in clinical trials, but scientific and logistical challenges remain. No approved vaccine exists yet, though novel approaches, including oral pills, are advancing development.
A multicenter US study highlights the devastating burden of influenza-associated acute necrotizing encephalopathy in children, with high mortality and disability rates despite aggressive therapy, underscoring the urgent need for prevention
A 29-year genomic study reveals increasing genetic diversity and prevalence of triazole-resistant Aspergillus fumigatus, raising concerns for clinical management and highlighting the need for novel diagnostics and antifungal strategies.
A study published in Pediatrics reveals low rates of hepatitis C treatment among children, highlighting significant racial disparities and access challenges.
New infectious diseases continue to emerge and old ones resurge due to evolving pathogens, environmental changes, and global interconnectedness. Understanding these dynamics is key to prevention and response.
A deep dive into humanity’s ongoing struggle with viruses and microbes—what science reveals, common myths, and how we can best protect ourselves.
Research presented at the European Respiratory Society’s annual meeting links early antibiotic use in children to increased allergy risks such as eczema and hay fever.
Antibiotic resistance is growing worldwide, threatening our ability to treat common infections. Discover the science, misconceptions, and what we can all do to combat superbugs.
Obesity influences the long-term effects of SARS-CoV-2, revealing diverse outcomes in primates and suggesting broader implications for humans.
Title: When Routine Health Practices Turn Risky: A Closer Look at Nasal Irrigation and Primary...