Highlight
– Lesion size in early atrophic AMD correlates strongly with localized visual sensitivity impairment measured by fundus-controlled perimetry (FCP).
– The proximity of atrophic lesions to the fovea critically determines central visual acuity and reading performance.
– Functional assessments targeting lesions provide sensitive and domain-specific evaluation, complementing structural imaging.
– These findings support tailored FCP as an effective endpoint for monitoring disease progression and guiding interventions in early atrophic AMD.