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Prevalence and Characteristics of Null Studies in Ophthalmology: A Comprehensive Analysis from 2014 to 2025
newsophthalmology researchpublication bias

Prevalence and Characteristics of Null Studies in Ophthalmology: A Comprehensive Analysis from 2014 to 2025

By MedXY|Sep 5, 2026

A large-scale PubMed analysis reveals that one in five ophthalmology studies report null primary outcomes, with declining prevalence over time and notable differences in funding, design, and journal impact between null and positive studies.

Impact of Neighborhood Socioeconomic Deprivation on Diabetic Retinopathy Screening Adherence in Medicare Beneficiaries
Diabetes & EndocrinologyArea Deprivation Indexretinopathy đái tháo đường

Impact of Neighborhood Socioeconomic Deprivation on Diabetic Retinopathy Screening Adherence in Medicare Beneficiaries

By MedXY|Sep 1, 2026

Increasing neighborhood socioeconomic deprivation is associated with reduced adherence to annual diabetic retinopathy screening among Medicare patients, highlighting disparities in preventive eye care.

Long-Term Incidence and Risk Factors for Glaucoma: Insights from the Gangnam Eye Cohort Study
newscohort studyglaucoma

Long-Term Incidence and Risk Factors for Glaucoma: Insights from the Gangnam Eye Cohort Study

By MedXY|Aug 31, 2026

A 10-year Korean cohort study reveals that retinal arteriosclerosis, intraocular pressure, age, serum uric acid, and cholesterol levels significantly increase the risk of structural glaucoma conversion.

Digital Defocus Vision Training Using Virtual Reality for Myopia Control: Current Evidence and Clinical Implications
Clinical Updatesmyopia controldigital defocus vision training

Digital Defocus Vision Training Using Virtual Reality for Myopia Control: Current Evidence and Clinical Implications

By MedXY|Aug 31, 2026

Virtual reality-based digital defocus vision training (DDVT) shows promise as a home-based adjunct to slow myopia progression in children, with randomized trial data demonstrating modest reductions in axial length and refractive error progr

Evaluating HOTV Versus Tumbling E Vision Tests for Effective Pediatric Screening
newsPediatric Vision Screeningamblyopia detection

Evaluating HOTV Versus Tumbling E Vision Tests for Effective Pediatric Screening

By MedXY|Aug 31, 2026

This study compares HOTV and tumbling E vision tests in children aged 3 to 15, demonstrating HOTV’s superior accuracy and suitability for children under 8, potentially reducing unnecessary referrals in pediatric vision screening.

Beyond Vision Loss: Psychosocial Factors Influencing Psychological Distress in Primary Open-Angle Glaucoma
newsprimary open-angle glaucomapsychological distress

Beyond Vision Loss: Psychosocial Factors Influencing Psychological Distress in Primary Open-Angle Glaucoma

By MedXY|Aug 31, 2026

This study reveals psychosocial factors such as social support and self-efficacy significantly influence psychological distress in primary open-angle glaucoma, beyond clinical disease measures.

IOP Stress Testing Identifies Glaucoma Eyes at Risk of Fast Progression Despite Controlled Office Pressure
newsvisual fieldIOP stress test

IOP Stress Testing Identifies Glaucoma Eyes at Risk of Fast Progression Despite Controlled Office Pressure

By MedXY|Aug 28, 2026

A stress test measuring intraocular pressure identifies glaucoma patients at risk of rapid progression despite normal office pressure readings, offering complementary prognostic insights beyond routine checks.

Intraday Upper Blepharoplasty Closure: Comparing Intradermal and Continuous Sutures for Optimal Outcomes
newsintradermal suturesscar aesthetics

Intraday Upper Blepharoplasty Closure: Comparing Intradermal and Continuous Sutures for Optimal Outcomes

By MedXY|Aug 27, 2026

This paired-eye randomized study evaluates the aesthetic results of intradermal versus continuous external sutures in upper blepharoplasty, revealing similar long-term scar quality and high patient satisfaction.

Long-Term Efficacy and Visual Field Outcomes of Selective Laser Trabeculoplasty in Glaucoma Management
newsvisual field progressionglaucoma

Long-Term Efficacy and Visual Field Outcomes of Selective Laser Trabeculoplasty in Glaucoma Management

By MedXY|Aug 26, 2026

This study evaluates long-term outcomes of selective laser trabeculoplasty (SLT) in controlling intraocular pressure and preventing visual field deterioration, identifying clinical factors influencing effectiveness and progression risk.

Immune-Mediated Disorders and Central Serous Chorioretinopathy: Clinical Insights from the MICRoN Report 21
Allergy & ImmunologyVisual Outcomesretinal imaging

Immune-Mediated Disorders and Central Serous Chorioretinopathy: Clinical Insights from the MICRoN Report 21

By MedXY|Aug 26, 2026

This study reveals that central serous chorioretinopathy (CSCR) in patients with immune-mediated disorders exhibits distinct clinical and imaging features, with immune-mediated status linked to poorer visual outcomes and higher recurrence,

Teprotumumab Versus Intravenous Glucocorticoids in Thyroid Eye Disease: Insights from a Japanese MRI Study
Diabetes & EndocrinologyMRITeprotumumab

Teprotumumab Versus Intravenous Glucocorticoids in Thyroid Eye Disease: Insights from a Japanese MRI Study

By MedXY|Aug 26, 2026

This study evaluates teprotumumab’s effectiveness for thyroid eye disease in Japanese patients, revealing notable improvements in orbital inflammation and proptosis compared to intravenous glucocorticoid therapy with distinct MRI-base

AI Writing Vocabulary in Ophthalmology: Faster Non-Native Adoption, Unchanged Outcomes
AIophthalmologyAI writing

AI Writing Vocabulary in Ophthalmology: Faster Non-Native Adoption, Unchanged Outcomes

By MedXY|Aug 25, 2026

This study examines the increased use of AI-associated writing vocabulary in ophthalmology articles, revealing faster adoption by non-native English authors without changes in publication frequency or journal quality.

Temporal Dynamics of Posterior Segment Imaging in Ocular Syphilis: Clinical Correlates and Laboratory Insights
Infectious Diseases光学干渉断層撮影Ocular syphilis

Temporal Dynamics of Posterior Segment Imaging in Ocular Syphilis: Clinical Correlates and Laboratory Insights

By MedXY|Aug 25, 2026

This study elucidates distinct temporal patterns of posterior segment imaging features in ocular syphilis correlated with symptom duration and laboratory markers, enhancing diagnostic timing and clinical interpretation.

Malignancy Risk after Ophthalmic Herpes Infection within a Diverse United States Cohort: Clinical Insights and Implications
Clinical UpdatesHerpes Zoster OphthalmicusHerpes Simplex Virus

Malignancy Risk after Ophthalmic Herpes Infection within a Diverse United States Cohort: Clinical Insights and Implications

By MedXY|Aug 25, 2026

Ophthalmic herpes infections generally do not increase overall malignancy risk, but herpes zoster ophthalmicus (HZO) elevates cancer risk in patients with immune dysregulation, underscoring the need for tailored oncologic vigilance.

Long-Term Outcomes of Strabismus Surgery in Children with Perinatal Brain Injury: Insights and Clinical Implications
newspediatric ophthalmologyStrabismus

Long-Term Outcomes of Strabismus Surgery in Children with Perinatal Brain Injury: Insights and Clinical Implications

By MedXY|Aug 24, 2026

Children with perinatal brain injury exhibit lower long-term success rates following strabismus surgery, mainly due to undercorrection despite comparable surgical dosing. Larger preoperative deviations predict poorer outcomes, underscoring

Novel Peripheral Retinal Vascular Biomarker on Ultra-Widefield OCTA Enables Severity Grading in Retinitis Pigmentosa
newsperipheral retinal vasculatureultra-widefield OCT angiography

Novel Peripheral Retinal Vascular Biomarker on Ultra-Widefield OCTA Enables Severity Grading in Retinitis Pigmentosa

By MedXY|Aug 24, 2026

Ultra-widefield OCT angiography identifies distinct peripheral retinal vascular phenotypes and a quantitative CNZ biomarker, facilitating an objective four-stage grading system for retinitis pigmentosa severity assessment and clinical trial

Central Geographic Atrophy Extent Predicts Vision-Related Quality of Life in Age-Related Macular Degeneration
newsVision-Related Quality of Liferetinal imaging

Central Geographic Atrophy Extent Predicts Vision-Related Quality of Life in Age-Related Macular Degeneration

By MedXY|Aug 24, 2026

Vision-related quality of life in geographic atrophy secondary to AMD is most strongly linked to lesion extent within a 2.5-mm central retinal zone, emphasizing targeted structural assessment for functional impact.

Impact of Trabeculectomy versus Medical Therapy on Visual Field and Quality of Life in Advanced Glaucoma: Insights from the TAGS Study
newstreatment outcomesglaucoma

Impact of Trabeculectomy versus Medical Therapy on Visual Field and Quality of Life in Advanced Glaucoma: Insights from the TAGS Study

By MedXY|Aug 24, 2026

The TAGS Study shows trabeculectomy slows visual field loss more effectively than medical treatment in advanced glaucoma, yet this did not translate into significant quality-of-life improvements over five years, highlighting limitations in

Distinct Geographic Atrophy Phenotypes in AMD: Characterizing Growth Patterns and Clinical Implications
newsFundus AutofluorescencePhenotypes

Distinct Geographic Atrophy Phenotypes in AMD: Characterizing Growth Patterns and Clinical Implications

By MedXY|Aug 23, 2026

This study identifies three candidate geographic atrophy phenotypes in age-related macular degeneration, revealing distinct growth rates and severity, with implications for prognosis and clinical trials.

Ultra-Long-Distance Robotic-Assisted Subretinal Injection for Submacular Hemorrhage: A Case Report
newssubmacular hemorrhagetelemedicine

Ultra-Long-Distance Robotic-Assisted Subretinal Injection for Submacular Hemorrhage: A Case Report

By MedXY|Aug 23, 2026

This report describes the successful ultra-long-distance robotic-assisted subretinal injection of recombinant tissue plasminogen activator for submacular hemorrhage, demonstrating procedural feasibility and safety across 4000 km.

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