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A 40-year retrospective study of 569 patients with ocular metastases reveals persistently poor survival, dominated by breast and lung primaries, with vision often preserved through treatment despite no significant survival improvements over
This study validates the prognostic accuracy of the 15-gene expression profiling (15-GEP) and PRAME assay in uveal melanoma patients irrespective of confirmatory cytopathology, supporting its use in clinical management when cytopathology is
Corrective lens spending affects nearly 20% of the US population, with half paying fully out-of-pocket, highlighting substantial financial burdens and access barriers. Evidence from clinical trials and epidemiologic studies underscores cost
This study reports durable tumor control and meaningful visual preservation up to 20 years after 103Pd plaque brachytherapy for choroidal melanoma, providing valuable long-term data for clinical decision-making.
A multisociety task force finds routine high-level disinfection (HLD) of reusable ophthalmic devices unnecessary in most clinics, recommends targeted HLD only for higher-risk encounters, and urges alignment of regulations with evidence.
A multi-center RCT assessing the adjunctive use of the Paro-ComPas app in periodontal care found no significant overall benefit, though moderate app engagement showed potential for improved plaque control.
More than one-third of Hispanic/Latino adults with diabetes exhibit diabetic retinopathy (DR), with significant variability across backgrounds. Hypertension notably associates with DR and vision-threatening DR, highlighting the need for tar
A thorough secondary analysis of a randomized clinical trial reveals no significant association between cornea donor diabetes severity and graft success, endothelial cell loss, or morphometric parameters at 1 year post-DMEK, supporting the
CDK4/6 inhibitor therapy in hormone receptor-positive breast cancer is linked to increased corneal epithelial alterations, including punctate epitheliopathy and vortex keratopathy, independent of aromatase inhibitor effects or tear film dys
Mitomycin C applied via injection or sponge during trabeculectomy offers comparable intraocular pressure control and safety, with injection potentially yielding more favorable bleb morphology and fewer postoperative interventions.
An open-label trial demonstrates the safety and potential efficacy of ChrimsonR-based optogenetic therapy combined with specialized goggles to enhance light sensitivity in patients with advanced retinitis pigmentosa, offering promising aven
PCSK9 inhibitors significantly reduce the risk of retinal vascular occlusions compared to other lipid-lowering therapies in patients with hyperlipidemia, highlighting their potential as a neuroprotective cardiovascular intervention.
This study reveals a significant increase in female representation among American Board of Ophthalmology oral board examiners following the transition to virtual exams, while the proportion of female examinees remained stable from 2011 to 2
The ELZA-sub400 protocol demonstrates safe and effective high-fluence corneal cross-linking tailored for ultrathin keratoconus corneas, halting ectasia progression in most treated eyes at 12 months with no endothelial damage.
This study compares retreatment rates and timing in retinopathy of prematurity among infants treated with intravitreal bevacizumab versus laser therapy, highlighting lower early retreatment rates and delayed intervention in the bevacizumab
This study elucidates the intricate three-dimensional morphology and cellular organization of outer retinal tubulation (ORT) in Bietti crystalline dystrophy, revealing structural reorganization of residual outer retina with potential implic
This randomized trial compares aflibercept monotherapy versus combined with reduced-fluence photodynamic therapy for PCV, highlighting OCTA metrics that predict polypoidal lesion closure and treatment response over 52 weeks.
Ultra-widefield swept-source OCT excels in assessing small-to-medium choroidal tumors, outperforming SD-OCT and providing detailed structural insights with noninvasive precision, though larger or complex tumors benefit from multimodal imagi
Ocular proton therapy in uveal melanoma induces significant reductions in corneal nerve parameters with partial recovery by 12 months, while corneal sensitivity remains stable and patient-reported symptoms show limited correlation with stru
This retrospective cohort study indicates that menopausal hormone therapy (MHT) is associated with increased risks of strabismus diagnosis and surgery but not reoperation in menopausal women, revealing significant ocular alignment considera
