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Gastroenterology

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Gastroenterology

Unveiling Postpancreatectomy Hemorrhage: Bleeding Sources, Cryptogenic Events, and Predictors of Severity from a Large Cohort Analysis

This study of 1,722 pancreaticoduodenectomies identifies key bleeding sources and predictors for severe postpancreatectomy hemorrhage, highlighting the roles of bile leak and infection in patients with pancreatic fistula and redefining cryp

Oct 10, 2026
Gastroenterology

Multidisciplinary Late Sequelae Clinics in Managing Low Anterior Resection Syndrome: A Prospective Cohort Study

A prospective cohort study demonstrates that a specialized multidisciplinary approach combining surgical and gastroenterological treatments significantly improves bowel function and quality of life in patients with low anterior resection sy

Oct 10, 2026Sign in to read
Gastroenterology

Modulating MASLD Risk in PNPLA3I148M Carriers: The Role of Gut Microbiota and Ceramides

Genetic susceptibility to metabolic dysfunction-associated steatotic liver disease (MASLD) is amplified by gut microbiota interactions, with ceramides playing a key role; targeted microbial interventions can reverse hepatic injury in at-ris

Oct 10, 2026Sign in to read
Gastroenterology

Comparing Side-to-Side and End-to-Side Gastrojejunostomy for Reducing Delayed Gastric Emptying After Pancreatoduodenectomy: Insights from the IPAD Randomized Trial

A randomized trial found no significant difference in delayed gastric emptying rates between side-to-side and end-to-side gastrojejunostomy after pancreatoduodenectomy, with comparable postoperative outcomes and quality of life.

Oct 10, 2026
Gastroenterology

Evaluating Gastrojejunostomy Techniques in Pancreatoduodenectomy: Side-to-Side vs End-to-Side Approaches and Impact on Delayed Gastric Emptying

The IPAD randomized trial shows no significant difference in delayed gastric emptying rates between side-to-side and end-to-side gastrojejunostomy after pancreatoduodenectomy, with comparable postoperative outcomes and quality of life.

Oct 9, 2026
Gastroenterology

Feasibility and Clinical Utility of Gastric Point-of-Care Ultrasound (G-POCUS) for Postoperative Gastric Content Assessment

This prospective pilot study demonstrates that gastric point-of-care ultrasound (G-POCUS) performed by trained nurses is a feasible, well-tolerated, and reliable method to assess gastric content in patients recovering from gastrointestinal

Oct 8, 2026
Gastroenterology

Peripheral Parenteral Nutrition Reduces Inflammation and Enhances Nutritional Recovery After Colorectal Surgery: Insights from a Randomized Trial

Early postoperative peripheral parenteral nutrition after colorectal resection reduces inflammatory markers and improves nitrogen balance without increasing complications, suggesting a beneficial supportive strategy in surgical recovery man

Oct 7, 2026
Gastroenterology

Impact of Medicaid Expansion on Survival in Colorectal Cancer with Liver Metastasis: A Population-Based Analysis

Medicaid expansion under the Affordable Care Act is associated with reduced mortality in patients under 65 diagnosed with colorectal cancer and synchronous liver metastasis, notably improving outcomes for those receiving surgical and system

Oct 6, 2026Sign in to read
Gastroenterology

High Efficacy and Tolerability of an 8-Week Bemnifosbuvir and Ruzasvir Regimen in Chronic Hepatitis C: Insights from a Phase 2 Study

An 8-week course of bemnifosbuvir and ruzasvir showed high sustained virologic response rates with excellent safety in treatment-naïve chronic hepatitis C patients across genotypes, including those with baseline resistance mutations.

Oct 5, 2026
Gastroenterology

Harnessing Circulating Tumour DNA for Minimal Residual Disease Detection in Colorectal Cancer: Insights from the INTERCEPT Programme

The INTERCEPT study demonstrates that longitudinal ctDNA testing effectively detects minimal residual disease post-curative treatment in colorectal cancer, enhancing recurrence prediction and refining risk stratification to guide future int

Oct 5, 2026
Gastroenterology

An Unexpected Cause of Severe Steatohepatitis in a Young Male

A 24-year-old obese male presents with incidental liver abnormalities; imaging reveals severe steatohepatitis with unusual features prompting detailed diagnostic evaluation and management strategies.

Oct 5, 2026
Diabetes & Endocrinology

Head-to-Head Comparison of Empagliflozin and Dapagliflozin on Liver Outcomes in Type 2 Diabetes with MASLD

A large Korean cohort study found similar hepatic benefits between empagliflozin and dapagliflozin in patients with type 2 diabetes and metabolic dysfunction-associated steatotic liver disease, with no difference in risk of severe liver com

Oct 5, 2026
Gastroenterology

Mitigating Innate Immune Response in Liver Transplantation: Insights from HOPE and NMP Machine Perfusion

This article reviews how hypothermic oxygenated and normothermic machine perfusion reduce hepatic and systemic inflammation after liver transplantation, improving immune regulation and clinical outcomes.

Oct 4, 2026
Gastroenterology

Impact of Medicaid Expansion on Adult Liver Transplant Outcomes: A Decade-Long Analysis

Medicaid expansion is associated with improved graft and patient survival following adult liver transplantation, highlighting the benefits of broader health insurance access on transplant outcomes.

Oct 2, 2026Sign in to read
Gastroenterology

Impaired Pulmonary Function and Dyspnea in Liver Transplant Recipients: Insights from a Nationwide Matched Cohort Study

This study reveals that liver transplant recipients exhibit significantly reduced lung function and increased dyspnea compared to the general population, highlighting the need for heightened pulmonary surveillance in this vulnerable group.

Oct 2, 2026
Gastroenterology

Advancing Donation After Circulatory Death Liver Transplants: Comparing Normothermic Machine and Regional Perfusion Outcomes

This study compares normothermic machine perfusion and normothermic regional perfusion in DCD liver transplants, demonstrating both advanced methods approach brain death graft survival and improve outcomes over static cold storage.

Oct 2, 2026Sign in to read
Gastroenterology

Chronic Steroid Use Does Not Increase Short-Term Risks After Distal Pancreatectomy: Insights from a Large National Database

A national propensity-matched analysis shows that chronic glucocorticoid use does not elevate 30-day morbidity or mortality after distal pancreatectomy, challenging perceptions of steroid-related surgical risk.

Sep 30, 2026
Gastroenterology

EUROSTAR/POQI Consensus: Standardising Care for Symptoms After Oesophago‑Gastric Resection

A concise summary of the EUROSTAR POQI consensus (Gut 2026) recommending standardized symptom monitoring, diagnostic criteria, investigation pathways and multidisciplinary services to manage common postoperative problems after oesophago‑gas

Sep 30, 2026
Diabetes & Endocrinology

Rapid Gastric Emptying in Postbariatric Hypoglycemia: Evaluating the Role of GLP-1 Receptor Agonists

Postbariatric hypoglycemia (PBH) is linked to rapid gastric emptying after Roux-en-Y gastric bypass. GLP-1 receptor agonists slow gastric emptying but do not prevent hypoglycemia, highlighting complex metabolic mechanisms in PBH management.

Sep 29, 2026
Gastroenterology

Nonoperative Management of Colonic Fistulas in Necrotizing Pancreatitis: Identifying Candidates for Conservative Care

Colonic fistulas in necrotizing pancreatitis do not always require surgery. Low-risk patients with lower BISAP scores may be successfully managed nonoperatively, reducing ICU stays and hospital length without compromising survival.

Sep 29, 2026
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