Section
A cohort study reveals that swimming-induced pulmonary edema (SIPE) is associated with transient mild cardiac dysfunction and elevated biomarkers, distinguishing it from asymptomatic swimmers and guiding acute assessment strategies.
Premeal insulin administration significantly lowers postprandial blood glucose and improves myocardial microvascular blood flow in young adults with type 1 diabetes, highlighting the importance of insulin timing for cardiovascular health.
A national cohort study found that adoption of the Resuscitation Quality Improvement (RQI) program for CPR training did not improve survival to discharge or return of spontaneous circulation in patients experiencing in-hospital cardiac arre
A cohort study demonstrates increased major cardiovascular event risk in first-degree relatives of individuals with high plasma lipoprotein(a), supporting cascade screening for targeted prevention.
This analysis of the China Rural Hypertension Control Project reveals that intensive blood pressure management chiefly drives cardiovascular risk reduction, with modest contributions from behavioral and metabolic changes, highlighting domai
A 5-generation French Canadian family with history of sudden cardiac death was diagnosed with calcium release deficiency syndrome using a novel burst pacing provocation test, illustrating its clinical utility and highlighting the importance
Risk-weighted apoB (RW-apoB) integrates LDL, TRL/remnants, and Lp(a) atherogenicity to improve coronary heart disease risk prediction, outperforming conventional lipid biomarkers like apoB and LDL-C in multiple population cohorts including
This study reveals that 21% of asymptomatic patients with mild HCM develop major adverse cardiovascular events over 7 years, highlighting key predictors such as age, symptom progression, and cardiac remodeling markers that inform management
Obicetrapib significantly lowers lipoprotein(a), LDL cholesterol, and apolipoprotein B in high cardiovascular risk patients, offering a promising addition to lipid-lowering therapies, especially for patients with mild to moderate Lp(a) elev
The SELUTION4ISR trial demonstrates that sirolimus-eluting balloons are a safe and effective noninferior alternative to standard care, including repeat drug-eluting stents, for treating coronary in-stent restenosis at 1 year.
Unsupervised clustering of echocardiographic and hemodynamic data in sepsis reveals four distinct cardiovascular subphenotypes, each with unique mortality risks and responses to treatment, enabling personalized shock management strategies.
A two-day stay at 2500 m altitude increases right ventricular afterload and impairs ventricular-arterial coupling but maintains oxygen delivery in stable pulmonary vascular disease patients.
Menaquinone-7 (MK-7) supplementation over two years significantly slows progression of coronary artery calcification (CAC) in symptomatic coronary artery disease patients, with favorable safety and potential implications for plaque stabiliz
The InEurHeart trial demonstrates that computed tomography-guided ventricular tachycardia ablation significantly reduces procedure duration while maintaining safety and efficacy compared to conventional methods in patients with ischemic car
Radiomic analysis of epicardial adipose tissue from routine cardiac CT scans enables robust, noninvasive early prediction of heart failure risk, enhancing conventional models and supporting precision prevention strategies.
Cerebral small vessel disease (SVD) significantly contributes to functional decline independently of bleeding or ischemic events during antithrombotic therapy, underscoring the need for targeted management strategies to address SVD burden i
Acoramidis stabilizes transthyretin and shows kidney-protective effects in transthyretin amyloid cardiomyopathy by reducing eGFR decline and albuminuria, with an initial reversible dip in kidney function associated with improved clinical ou
This review synthesizes evidence demonstrating that implementing full quadruple GDMT (ARNI, β-blockers, MRAs, SGLT2i) in HFrEF reduces hospitalization risks and healthcare costs, often yielding net savings despite medication expenses.
A novel risk score incorporating COPD and graded renal dysfunction improves prediction of one-year mortality post-TAVI, showing excellent internal validity but requiring external validation before clinical use.
In frail elderly Asian AF patients stable on warfarin, transitioning to DOACs increased risks of bleeding, thromboembolic events, and mortality, emphasizing cautious individualized management.
