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Oncology

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Venous Integrity as a Key Predictor of Nipple-Areolar Complex Necrosis Following Nipple-Sparing Mastectomy

This study highlights that venous injury significantly influences nipple-areolar complex necrosis risk after nipple-sparing mastectomy, with near-infrared imaging improving intraoperative risk assessment.

Sep 27, 2026
news

Venous Drainage Integrity as a Crucial Factor in Preventing Nipple-Areolar Complex Necrosis Post Nipple-Sparing Mastectomy: Insights from Cadaveric and Clinical Studies

This study reveals that venous injury significantly contributes to nipple-areolar complex necrosis after nipple-sparing mastectomy and presents a predictive model integrating near-infrared vein imaging with indocyanine green angiography to

Sep 27, 2026
Clinical Updates

Contemporary Surgical Management of Vulvar Cancer: Balancing Improved Survival with Increased Reoperation Rates — Insights from a Finnish Nationwide Study

This review synthesizes evidence that modern personalized surgical strategies for vulvar squamous cell carcinoma enhance survival outcomes despite higher reoperation rates, emphasizing evolving surgical techniques, sentinel lymph node biops

Sep 27, 2026Sign in to read
news

Prepectoral vs. Subpectoral Breast Reconstruction After Radiotherapy: A Prospective Long-Term Outcome Analysis

This prospective study compares long-term outcomes of prepectoral and subpectoral implant breast reconstructions in post-mastectomy radiotherapy patients, revealing similar complication rates and quality-of-life measures, with patient facto

Sep 27, 2026
Hematology-Oncology

Decoding Large B Cell Lymphoma Heterogeneity: A Single-Cell Atlas Identifies Malignant Archetypes Linked to Patient Outcomes

A comprehensive single-cell RNA sequencing study of large B cell lymphomas reveals five malignant B cell archetypes, with one subtype predictive of poor treatment response and survival, paving the way for precision therapy in LBCL.

Sep 26, 2026
Hematology-Oncology

Personalizing Allogeneic Hematopoietic Cell Transplantation in Adult AML Using Measurable Residual Disease Testing

Measurable residual disease (MRD) testing offers critical insights to tailor allogeneic hematopoietic cell transplantation in adults with acute myeloid leukemia, optimizing patient selection, conditioning intensity, and relapse surveillance

Sep 26, 2026Sign in to read
news

Optimizing Management of Conjunctival Melanocytic Lesions: A Sequential Multimodal Treatment Framework

A retrospective cohort study demonstrates that a tailored, stepwise multimodal approach effectively controls conjunctival melanocytic lesions with reduced recurrence and metastasis risks, guided by lesion grade and clinical features.

Sep 26, 2026Sign in to read
news

Long-Term Airway Outcomes and Mortality Risks in Laryngeal Chondrosarcoma: Balancing Preservation and Oncological Control

This retrospective study highlights the risk of airway complications and mortality in laryngeal chondrosarcoma patients managed with function-preserving surgery, emphasizing the need for vigilant surveillance and tailored treatments.

Sep 26, 2026
news

EHR-Integrated Synoptic Operative Reporting: Enhancing Documentation in Head and Neck Oncologic Surgery

This study evaluates the development, implementation, and performance of EHR-integrated synoptic operative reporting templates in head and neck cancer surgery, highlighting improved documentation quality and variable adherence.

Sep 26, 2026Sign in to read
Gastroenterology

Nationwide Dutch Study Reveals Limited Prior Endoscopic Surveillance in Barrett’s Esophagus-Related Dysplasia and Cancer Diagnosis

In a large Dutch cohort, 90% of patients with Barrett’s esophagus-related dysplasia or cancer had no prior endoscopic surveillance, highlighting a critical gap in early detection and the need for evidence-based screening strategies.

Sep 26, 2026Sign in to read
Gastroenterology

Decoding Steatohepatitic Hepatocellular Carcinoma: Multi-Omics Insights and Emerging Diagnostic-Therapeutic Pathways

This study integrates multi-omics data to characterize steatohepatitic hepatocellular carcinoma (SH-HCC), establishing robust diagnostic models and identifying FABP4 as a promising therapeutic target, with implications for personalized mana

Sep 26, 2026
news

Evaluating the Impact of Palliative Radiotherapy Timing on End-of-Life Care in Gynecologic Malignancies

This study highlights how timing of palliative radiotherapy in gynecologic cancers influences end-of-life care quality, with late radiation associated with less aggressive care and better supportive outcomes compared to radiation administer

Sep 25, 2026
news

Advancing Sentinel Lymph Node Biopsy in Vulvar Cancer: Real-Time Near-Infrared Fluorescence Imaging Enhances Detection and Safety

A recent study demonstrates the feasibility and safety of hybrid indocyanine green and technetium-99m nanoparticle fluorescence imaging for sentinel lymph node biopsy in early-stage vulvar cancer, improving detection rates and oncologic out

Sep 25, 2026
news

Disparities in Ovarian Cancer Clinical Trial Access Linked to Social Vulnerability: A U.S. County-Level Analysis

County-level social vulnerability significantly limits ovarian cancer clinical trial availability, underscoring structural inequities and the need for targeted strategies to improve trial access in vulnerable communities.

Sep 25, 2026Sign in to read
Hematology-Oncology

Targeting IGF2BP2: A Novel Therapeutic Avenue in Peripheral T-cell Lymphoma Through RNA Modification and Immune Modulation

This article explores the pivotal role of IGF2BP2, an N6-methyladenosine reader, in driving tumor growth and immune evasion in peripheral T-cell lymphoma, highlighting its potential as a dual-action therapeutic target.

Sep 24, 2026
news

Cost-Effectiveness of Thoracentesis with Pleural Fluid Cytology Versus Thoracoscopy with Pleural Biopsy in Diagnosing Malignant Pleural Effusion

This study evaluates when thoracentesis or thoracoscopy is more cost-effective in diagnosing malignant pleural effusion in patients with prior or active malignancy, highlighting thresholds of pleural fluid cytology sensitivity guiding optim

Sep 24, 2026
Gastroenterology

Neurotensin Receptor 1: A Key Driver of Immune Exclusion and Poor Prognosis in Colorectal Cancer

High expression of neurotensin receptor 1 (NTSR1) defines an immune-cold colorectal cancer subtype linked to worse outcomes by creating mechanical and biological barriers that exclude T-cell infiltration, highlighting a novel immunotherapeu

Sep 23, 2026Sign in to read
Clinical Updates

Centralized Multidisciplinary Retinoblastoma Care: Closing Outcome Gaps in Resource-Limited Settings with Telemedicine and Advanced Globe Salvage

Centralized multidisciplinary retinoblastoma care incorporating telemedicine and international partnership at KHCC improved survival and globe salvage rates to levels comparable with high-income countries, demonstrating a scalable model for

Sep 23, 2026
news

Lymphovascular Invasion as an Independent Prognostic Marker in Laryngeal Squamous Cell Carcinoma: Insights from a National Cohort Study

Lymphovascular invasion independently predicts worse overall survival in surgically treated laryngeal squamous cell carcinoma, influencing postoperative risk stratification and adjuvant therapy decisions.

Sep 23, 2026
Clinical Updates

Standalone Salpingectomy for Primary Ovarian Cancer Prevention: A Cost-Effectiveness Analysis

This review synthesizes evidence on the cost-effectiveness of standalone salpingectomy for ovarian cancer prevention, highlighting its benefits primarily in women at moderately elevated risk, especially between ages 45-50, supporting tailor

Sep 23, 2026
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