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A randomized clinical trial demonstrated that the 5x-multiplier algorithm significantly reduces opioid prescriptions at discharge without increasing consumption, refill rates, or patient dissatisfaction after major abdominal cancer surgery
This study compares radiographic versus pathology-integrated response metrics to identify optimal surgical timing after neoadjuvant imatinib treatment in KIT exon 11-mutant gastrointestinal stromal tumors (GIST). Pathology measures indicate
This article reviews advances in liver xenotransplantation using genetically modified porcine organs as a bridging strategy for acute liver failure, highlighting recent clinical progress, challenges, and future directions.
Quantitative measurement of beta-trace protein in nasal sponge extracts accurately identifies postoperative cerebrospinal fluid leaks after endoscopic endonasal surgery for sellar tumors, enabling early diagnosis and targeted intervention.
This pooled analysis evaluates the safety and effectiveness of the Colovac Anastomosis Protection Device compared to standard diverting loop ileostomy following low anterior resection for rectal cancer, showing comparable major complication
A Swedish national retrospective study reveals that liver transplantations initiated between 17:00 and 05:59 are linked to significantly increased postoperative complications and healthcare costs, highlighting the need for optimized schedul
This meta-analysis of four RCTs compares cold and hot snare polypectomy for large colorectal polyps, demonstrating lower major adverse events but higher recurrence with cold resection, especially in adenomas with high-grade dysplasia.
The Integrative Muscle-Adipose Score (IMAS) combines muscle and fat measures into a sex-specific tool that accurately predicts long-term survival and postoperative complications in liver transplant recipients, outperforming existing models.
This study highlights the diagnostic and therapeutic value of angiography in intraluminal postpancreatoduodenectomy hemorrhage, revealing its superiority in bleeding source localization and effective hemostasis compared to other modalities.
RESTORE II RCT demonstrates that a 12-week multidisciplinary rehabilitation program significantly improves cardiorespiratory fitness in survivors of upper gastrointestinal cancer surgery, supporting its integration in post-oncologic care.
This study compares long-term outcomes of endovascular versus open bypass interventions for femoropopliteal disease in patients with claudication, finding similar rates of major adverse limb events and progression to critical limb ischemia
This study suggests intraoperative botulinum toxin may reduce sialocele formation after parotidectomy, though larger prospective trials are needed to confirm efficacy and guide clinical use.
A clear, imaging-centered framework for diagnosing and stratifying appendiceal abscesses—introducing anatomotopographic localization, the Jeffrey radiological grading, and pathway-based imaging recommendations to harmonize practice.
An analysis of elective endovascular repair outcomes in nonagenarians shows similar 30-day mortality to younger patients, supporting individualized treatment decisions based on risk rather than age alone.
This study reveals that over one-third of patients with localized PDAC receiving neoadjuvant therapy and surgery achieve actual five-year survival, highlighting the impact of early systemic failure and identifying factors predicting long-te
This study analyzes how the balance between operative and nonoperative management in emergency general surgery for older adults relates to their odds of discharge home, proposing ONR as a novel quality benchmark beyond traditional metrics.
A randomized clinical trial demonstrates that synthetic mesh reinforcement during subcostal abdominal closure notably decreases incisional hernia incidence without increasing postoperative complications, improving patient recovery after hep
This analysis of localized appendiceal adenocarcinoma reveals low relapse rates post-resection, identifies key histopathologic and molecular relapse predictors, and finds no significant benefit from adjuvant chemotherapy, challenging conven
This study employs interpretable anomaly-detection algorithms to identify high-risk phenotypes in resected solid pseudopapillary pancreatic tumors, overcoming limitations of conventional survival models in ultra-rare cancer-specific deaths.
In elderly patients with locally advanced esophageal squamous cell carcinoma, neoadjuvant immunochemoradiotherapy offers superior tumor response but increases surgical complexity and cardiac risks compared to immunochemotherapy. Personalize
