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This multicenter randomized clinical trial demonstrates that fiber-based near-infrared autofluorescence (NIRAF) enhances intraoperative parathyroid gland identification during thyroidectomy and bilateral parathyroidectomy without increasing
A randomized clinical trial in Uganda compared standard open anterior mesh repair with a modified technique addressing femoral hernias, demonstrating both methods as safe and effective options for women’s groin hernia repair in low-re
The CONKO-007 trial reveals that adding chemoradiotherapy after induction chemotherapy increases margin-negative (R0) resections in surgically treated unresectable pancreatic cancer but does not improve overall survival.
A nationwide Danish study reveals that while 40% of left-sided infective endocarditis patients have surgical indications, only half undergo surgery. Those receiving surgery are younger, less comorbid, and show improved survival, underscorin
A large randomized trial shows that ivabradine, despite effectively lowering heart rate during surgery, does not reduce myocardial injury after noncardiac surgery, highlighting the complexity of perioperative cardiac risk management.
The MITRACURE international registry reveals that mitral valve surgery patients often present late in disease progression with advanced symptoms, showing modest repair rates and notable in-hospital mortality, underscoring the need for earli
A randomized trial demonstrates that iodine-impregnated drapes significantly reduce pocket contamination and cardiac implantable electronic device infections in repeat surgeries, offering a simple, cost-effective prophylactic intervention.
A prospective study reveals that nearly 20% of surgical patients experience postoperative delirium in the PACU, with elevated preoperative anxiety significantly increasing this risk. Implementation of a brain health care bundle improves man
A six-year-old boy nearly lost his leg after stepping on a dead fish infected with Vibrio vulnificus. This article explores the bacteria’s risks, prevention, symptoms, and expert advice for safe seaside outings.
This multicenter randomized trial demonstrates that electroacupuncture reduces postoperative ileus duration and accelerates gastrointestinal recovery after laparoscopic gastrectomy for gastric cancer, outperforming sham and standard care.
A French multicentre trial showed single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) achieved superior weight loss compared to Roux-en-Y gastric bypass (RYGB) at 2 years, with similar safety profiles.
This multicenter study identifies key predictors of diabetes outcomes one year after total pancreatectomy with islet autotransplantation, highlighting the importance of preoperative glycemic control and age in achieving insulin independence
A comprehensive Nordic trial reveals that postoperative nasogastric tube removal may increase anastomotic leak risk after oesophagectomy, suggesting continued use of NG tubes for patient safety.
The NETSARC+ registry study comprehensively characterizes liposarcoma histotypes, revealing diverse clinical presentations, management strategies, and prognoses, with dedifferentiated liposarcoma having the poorest survival and age-sex spec
This nationwide Korean cohort study found that hysterectomy is associated with a modestly increased risk of developing hypertension in women aged 40 to 59 years, particularly in those with elevated post-surgical hemoglobin levels and after
Perioperative nitric oxide administration in CKD patients undergoing cardiac surgery significantly reduces acute kidney injury incidence and preserves renal function, while demonstrating safety and additional benefits against postoperative
This prespecified analysis of the MINT trial evaluates how liberal versus restrictive red blood cell transfusion strategies affect 30-day outcomes in acute MI patients, focusing on those undergoing revascularization, revealing nuanced risk
The SPYRAL HTN-ON MED trial demonstrates that renal denervation provides significant long-term reductions in both ambulatory and office systolic blood pressure with good safety, supporting its role in managing hypertension.
A multicenter randomized trial shows POEM is non-inferior to LHM plus Dor fundoplication for achalasia symptom control at 5 years, with differing reflux profiles.
Total neoadjuvant therapy combined with watch-and-wait strategies achieves a 37% clinical complete response rate in locally advanced rectal cancer with manageable toxicity, offering an organ-preserving alternative to surgery.
