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Superintelligence

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Superintelligence

Stepped Care Plus Cash Incentives Cuts 3‑Year Diabetes Incidence in Multiethnic Asian Prediabetes Cohort

The Pre-DICTED randomized trial found a stepped-care diabetes prevention program augmented with financial incentives reduced 3‑year diabetes conversion (34.8% vs 47.3%; adjusted RR 0.74), with metformin added for persistent high-risk partic

Nov 17, 2025Sign in to read
Superintelligence

Does AI Make Endoscopists Lazy? New Multicentre Data Show Reduced Adenoma Detection After AI Exposure

A multicentre observational study reports a 6% absolute fall in adenoma detection rate for non‑AI colonoscopies after clinicians were exposed to AI-assisted polyp detection—raising concerns about endoscopist deskilling and the need for safe

Nov 9, 2025
Superintelligence

Wearable Monitoring Shows Sustained Increases in Daily Activity After Total Knee Arthroplasty, with a 6‑Month Recovery Window

A prospective cohort using Apple Watch data demonstrated meaningful increases in step count, standing time and gait speed after unilateral total knee arthroplasty, peaking at 6 months and persisting at 12 months.

Nov 5, 2025
Superintelligence

How Eli Lilly and NVIDIA’s AI Supercomputer is Revolutionizing Drug Discovery

Eli Lilly and NVIDIA have partnered to launch the largest AI-powered supercomputing platform in pharma, aiming to accelerate drug discovery, personalize medicine, and enhance manufacturing through unprecedented computational power.

Nov 4, 2025
Superintelligence

AI-RAPNO: Translating Artificial Intelligence into Reliable Response Assessment for Pediatric Neuro-Oncology

AI-RAPNO synthesizes current AI developments for pediatric brain tumour imaging and provides practical recommendations to improve trustworthiness, generalisability, and clinical implementation of AI-driven response assessment using the RAPN

Nov 4, 2025Sign in to read
Superintelligence

Digital‑Twin Decision Aid for Knee Osteoarthritis Improves Decision Quality and 6‑Month Function: Randomized Trial Results

An AI-enabled decision aid that generated patient-specific digital twins improved decision quality, reduced decisional conflict and regret, and produced better 6–9 month knee function versus education alone in patients considering total kne

Nov 1, 2025
Superintelligence

Evaluating AI-Led vs Human-Led Lifestyle Interventions in Prediabetes: Evidence from a Randomized Clinical Trial of the Diabetes Prevention Program

This review examines the first phase 3 randomized trial demonstrating that an AI-powered Diabetes Prevention Program lifestyle intervention is noninferior to human coaching in improving weight loss, HbA1c, and physical activity among adults

Oct 29, 2025Sign in to read
Superintelligence

Harnessing Cancer-Testis Antigens for Precision Immunotherapy in Head and Neck Cancer

This study identifies specific cancer-testis antigens (CTAs) as promising targets for personalized immunotherapy in head and neck squamous cell carcinoma (HNSCC), validated across multiomic datasets to enhance therapeutic precision.

Oct 24, 2025
Superintelligence

Harnessing Wearable Technology to Boost Cardiac Rehabilitation Adherence in CHD Patients: Insights from a Randomized Trial

This study evaluates how smartwatch-assisted home-based cardiac rehab improves exercise adherence and health outcomes in coronary heart disease patients.

Oct 23, 2025
Superintelligence

Revolutionizing Cardiac Rehab: The Impact of Wearable Technology and Online Coaching

This review discusses a landmark study demonstrating how wearable devices and online coaching improve exercise capacity in coronary artery disease patients, highlighting advancements in remote cardiac rehabilitation.

Oct 23, 2025
Superintelligence

Artificial Intelligence in Imaging-Based Extranodal Extension Detection: Advancing Prognostication in HPV-Positive Oropharyngeal Cancer

An AI-driven model accurately detects imaging-based extranodal extension in HPV-positive oropharyngeal cancer from CT scans, improving outcome prediction beyond expert radiologist assessments and identifying patients at higher risk of poore

Oct 22, 2025Sign in to read
Superintelligence

Advancing Early Pediatric Sepsis Detection: Machine Learning Models Predicting Onset Within 48 Hours

This study developed and validated machine learning models with high accuracy to predict early pediatric sepsis and septic shock within 48 hours using multisite electronic health record data in emergency departments.

Oct 21, 2025Sign in to read
Superintelligence

Medicare Advantage and Cancer Surgery Outcomes: Are Patients Being Routed Away from High-Quality Hospitals?

This retrospective national cohort study reveals that Medicare Advantage (MA) enrollees undergoing major cancer surgery are less likely to receive care at high-quality hospitals compared to traditional Medicare beneficiaries, raising concer

Oct 21, 2025
Superintelligence

Enhancing Melanoma Prognosis: AI-Driven Quantification of Tumor-Infiltrating Lymphocytes Outperforms Traditional Pathology

This study demonstrates that an AI algorithm provides more reproducible and prognostically relevant assessment of tumor-infiltrating lymphocytes in melanoma compared to traditional pathologist methods, offering a promising tool to improve c

Oct 21, 2025
Superintelligence

Artificial Intelligence-Detected Tumor-Infiltrating Lymphocytes as a Biomarker in Anti-PD-1-Based Therapy for Advanced Melanoma: Clinical Evidence and Translational Perspectives

AI-detected tumor-infiltrating lymphocytes on routine histology independently predict response and survival in advanced melanoma treated with anti-PD-1 therapies, outperforming manual scoring and offering an accessible biomarker for immune

Oct 21, 2025
Superintelligence

患者向けデジタルヘルス介入による肺がんスクリーニング受診率の向上:ランダム化比較試験からの洞察

デジタルヘルスプログラムは、高リスク個体の肺がんスクリーニング率を大幅に向上させ、予防医療の改善にデジタルツールの潜在力を示しています。

Oct 21, 2025
Superintelligence

Enhancing Lung Cancer Screening Uptake Through a Direct-to-Patient Digital Health Intervention: Insights from a Randomized Clinical Trial

A digital health program significantly increased lung cancer screening rates among high-risk individuals, underscoring digital tools’ potential to improve preventive care.

Oct 21, 2025Sign in to read
Superintelligence

Navigating the AI Revolution in Health Care: Insights from the JAMA Summit

Artificial intelligence is reshaping health care, offering vast potential benefits alongside significant challenges. The JAMA Summit emphasizes the need for robust evaluation, equitable deployment, and multi-stakeholder collaboration to ens

Oct 14, 2025
Superintelligence

Harnessing Artificial Intelligence for Diagnosing Sexually Transmitted Infections and Anogenital Dermatoses: Insights from a Systematic Review and Meta-Analysis

AI demonstrates high accuracy in identifying mpox and other anogenital conditions from clinical images, yet significant research gaps and validation needs remain before clinical adoption.

Oct 4, 2025
Superintelligence

Decoding Nonverbal Learning Disability in Children: Distinct Profiles and Their Clinical Implications

A cross-sectional study identifies four distinct profiles of nonverbal learning disability (NVLD) in children, revealing significant heterogeneity in visual-spatial deficits, academic skills, and psychiatric diagnoses, highlighting implicat

Oct 1, 2025
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