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The DANFLU-2 trial demonstrates that high-dose influenza vaccine reduces cardiovascular and cardiorespiratory hospitalizations compared to standard-dose in adults ≥65 years, with similar benefits across subgroups including heart failure and
The DAN-RSV trial demonstrates that RSV vaccination significantly lowers all-cause cardiorespiratory hospitalizations among older adults, suggesting vaccines may reduce infection-triggered cardiovascular complications and benefit chronic di
An 8-week cardiorespiratory exercise program initiated 2 months after ischemic stroke improved cognitive performance at 12 months, despite no significant preservation of hippocampal volume compared with control. The intervention was safe an
A community-based intervention using ventilation hoods during cooking reduced 24-hour PM2.5 exposure by nearly 30% and improved cardiometabolic and pulmonary health markers in rural Chinese villages reliant on wood fuel.
Long COVID patients exhibit distinct mitochondrial bioenergetic impairments, with altered ATP synthase function correlating with clinical symptoms and quality of life, implicating mitochondrial dysfunction in its pathogenesis.
This study establishes reliable FeNO reference values throughout life in respiratory healthy individuals, highlighting factors that influence nitric oxide levels and enhancing asthma diagnosis and management.
Rentosertib, an AI-designed TNIK inhibitor, demonstrated safety and preliminary efficacy in idiopathic pulmonary fibrosis in a randomized phase 2a trial, marking a milestone in AI-driven drug development for progressive lung diseases.
A national French study reveals that cold agglutinin syndrome (CAS) develops about 10 days after Mycoplasma pneumoniae infection onset, often requiring ICU care and transfusions, with a generally favorable prognosis despite frequent venous
This review synthesizes trial evidence showing that nicotine-containing e-cigarettes modestly improve lipid profiles but cause no significant changes in lung function or other cardiovascular markers compared to cigarette substitutes in smok
The ORCA-3 trial confirms cytisinicline’s efficacy and safety for smoking cessation at 6 and 12 weeks, showing sustained abstinence and reduced nicotine craving up to 24 weeks.
Analysis of WHO data reveals declining global pulmonary embolism mortality overall, with marked differences by region and income, highlighting urgent needs in lower-middle-income countries.
Exercise-induced dynamic hyperinflation in HFpEF patients is linked to elevated pulmonary capillary wedge pressure, suggesting altered lung mechanics contribute significantly to exercise intolerance beyond ventricular stiffness alone.
A large randomized clinical trial demonstrates that pulmonary rehabilitation using minimal equipment is noninferior to gym-based programs with specialist equipment for improving exercise capacity and quality of life in chronic respiratory d
This study demonstrates that asthma modestly increases the risk of degenerative valvular heart diseases, highlighting the need for cardiovascular vigilance in asthmatic individuals.
Kidney-transplant recipients on long-term kidney replacement therapy demonstrate significant reductions in COVID-19-related hospitalizations and mortality following three or more vaccine doses, supporting booster vaccinations in this vulner
Recent rhinovirus infection may nearly halve COVID-19 risk and reduce viral load by triggering airway antiviral gene expression, partially explaining children’s milder COVID-19 outcomes.
Observational data from the RECOVER Initiative suggest that SARS-CoV-2 reinfection raises the risk of long COVID by 35% relative to single infections, with more recent vaccination potentially mitigating this risk.
The Stratus variant, known as XFG, now dominates COVID-19 cases in the U.S., complicating recovery efforts amidst rising infections and changing vaccine guidance.
Inhaled molgramostim, a recombinant human GM-CSF, significantly improves lung gas transfer and quality of life in autoimmune pulmonary alveolar proteinosis, with safety comparable to placebo.
Long-term exposure to ambient air pollutants, notably nitrogen dioxide, is linked to increased asthma exacerbations in women, independent of plant-based diet adherence, underscoring the need for stricter air quality standards and targeted r
