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Age-Dependent Interplay of Modifiable Risk Factors and Genetic Risk in Pancreatic Cancer
newsgenetic risklifestyle risk factors

Age-Dependent Interplay of Modifiable Risk Factors and Genetic Risk in Pancreatic Cancer

By MedXY|May 15, 2026

A UK Biobank study found that lifestyle-related pancreatic cancer risks were strongest in younger adults, especially those with high genetic risk, supporting early prevention efforts.

Regional School-Based CPR Training With Low-Cost Manikin Delivered by School Nurses: The Home Multiplier Effect
newsbasic life supportcommunity nursing

Regional School-Based CPR Training With Low-Cost Manikin Delivered by School Nurses: The Home Multiplier Effect

By MedXY|May 18, 2026

A nurse-led school CPR program in Murcia, Spain, used low-cost manikins to train students and their families, creating a strong home-based multiplier effect and generally adequate basic life support performance.

How Historical Redlining and Modern Housing Discrimination Fuel Firearm Violence in Chicago
newsfirearm violencehousing discrimination

How Historical Redlining and Modern Housing Discrimination Fuel Firearm Violence in Chicago

By MedXY|May 13, 2026

A Chicago study found that historical redlining and current housing discrimination are both linked to higher firearm homicide rates in Black neighborhoods, highlighting housing justice as a key violence-prevention strategy.

Menopausal Hot Flushes and Night Sweats May Be Linked to Retirement: What an Australian Study Found
OB/GYN & Women's Healthhot flushesnight sweats

Menopausal Hot Flushes and Night Sweats May Be Linked to Retirement: What an Australian Study Found

By MedXY|Aug 18, 2026

A large Australian longitudinal study found that women with both hot flushes and night sweats had slightly higher odds of retirement, suggesting menopausal symptom burden may influence workforce participation.

Cerebral “Dirty-Appearing” White Matter and Its Link to Cognitive Decline and Dementia Risk
Neurologycognitive declineDementia

Cerebral “Dirty-Appearing” White Matter and Its Link to Cognitive Decline and Dementia Risk

By MedXY|May 13, 2026

In older adults with limited small vessel disease, “dirty-appearing” white matter on MRI was not linked to baseline cognition, cognitive decline, or dementia risk, unlike conventional white matter hyperintensities.

Staging Intermediate Hyperglycaemia to Improve Type 2 Diabetes Prevention: Findings from the ELSA-Brasil Study
Diabetes & Endocrinologydiabetes preventionfasting glucose

Staging Intermediate Hyperglycaemia to Improve Type 2 Diabetes Prevention: Findings from the ELSA-Brasil Study

By MedXY|May 13, 2026

The ELSA-Brasil study found that staging intermediate hyperglycaemia with fasting glucose plus 1-hour glucose better predicted type 2 diabetes than fasting glucose plus HbA1c, and a clinical risk score reduced unnecessary testing.

Weight Regain Can Reverse the Metabolic Benefits of Caloric Restriction: Insights From CALERIE-2
Diabetes & EndocrinologyCaloric RestrictionIGF-1

Weight Regain Can Reverse the Metabolic Benefits of Caloric Restriction: Insights From CALERIE-2

By MedXY|May 13, 2026

CALERIE-2 post hoc analysis found that weight regain after caloric restriction can reverse improvements in insulin and IGF-1 signaling, while sustained weight loss preserves metabolic benefits and may lower biological aging markers.

Rates of Systemic Treatment for Metastatic Non-Small Cell Lung Cancer Among Older Adults
newsbiomarker testingmetastatic NSCLC

Rates of Systemic Treatment for Metastatic Non-Small Cell Lung Cancer Among Older Adults

By MedXY|May 12, 2026

A population-based study of older adults with metastatic NSCLC found that fewer than half received systemic treatment, with only slight improvement over time. Oncology referral and biomarker testing were strongly linked to treatment, while

Systemic Treatment Remains Underused in Older Adults With Metastatic Non-Small Cell Lung Cancer
newsbiomarker testingmetastatic non-small cell lung cancer

Systemic Treatment Remains Underused in Older Adults With Metastatic Non-Small Cell Lung Cancer

By MedXY|May 12, 2026

A large SEER-Medicare study found that fewer than half of older adults with metastatic NSCLC received systemic therapy, with only modest improvement from 2006 to 2021. Specialist referral and biomarker testing were strongly linked to treatm

Obesity Counseling Is Still Missed in Most US Office Visits, With Older Adults Least Likely to Receive Advice
Family Medicine & NutritionNAMCSobesity counseling

Obesity Counseling Is Still Missed in Most US Office Visits, With Older Adults Least Likely to Receive Advice

By MedXY|May 12, 2026

A national analysis of US office visits found that obesity counseling remains uncommon, with only 40.1% of visits including any counseling and 12.2% including weight, diet, and exercise advice together.

Low-Dose Aspirin’s Pregnancy Benefit Appears Unchanged by Start Time or Adherence in a Large Multicentre Post Hoc Trial Analysis
OB/GYN & Women's HealthadherencePregnancy

Low-Dose Aspirin’s Pregnancy Benefit Appears Unchanged by Start Time or Adherence in a Large Multicentre Post Hoc Trial Analysis

By MedXY|Aug 18, 2026

In this post hoc analysis of a large randomized pregnancy trial, aspirin’s effects on preterm birth and perinatal mortality were not meaningfully modified by gestational age at initiation or measured adherence.

Weak Grip, Slow Walking Pace, and Sarcopenia Signal Higher Risk of Incident Stroke and Worse Poststroke Survival in UK Biobank
Neurologygrip strengthSarcopenia

Weak Grip, Slow Walking Pace, and Sarcopenia Signal Higher Risk of Incident Stroke and Worse Poststroke Survival in UK Biobank

By MedXY|May 10, 2026

In nearly 483,000 UK Biobank participants, sarcopenia, low grip strength, and slow walking pace were associated with higher risks of incident stroke and poorer survival after stroke.

Multi-ancestry Polygenic Risk Scores Substantially Improve Type 2 Diabetes Risk Prediction Across Diverse Populations
Diabetes & Endocrinologydiabetic complicationsmulti-ancestry

Multi-ancestry Polygenic Risk Scores Substantially Improve Type 2 Diabetes Risk Prediction Across Diverse Populations

By MedXY|May 10, 2026

A large multi-ancestry study shows that publicly available polygenic risk scores improve prediction of type 2 diabetes onset and selected microvascular complications across major global ancestry groups.

Household Income Decline and Job Loss Among Survivors of Critical Illness: A Nationwide Cohort Study
Critical Carecritical illnessICU survivorship

Household Income Decline and Job Loss Among Survivors of Critical Illness: A Nationwide Cohort Study

By MedXY|May 9, 2026

A large South Korean study reveals critical illness survivors face severe socioeconomic consequences, with 27.6% experiencing income decline and 12.3% job loss within a year, disproportionately affecting high-income households despite unive

Ethnicity Influences Relapse-Free Survival in Immune-Mediated Thrombotic Thrombocytopenic Purpura
Hematology-Oncologybệnh huyết họcethnic disparities

Ethnicity Influences Relapse-Free Survival in Immune-Mediated Thrombotic Thrombocytopenic Purpura

By MedXY|May 9, 2026

A French study reveals African ancestry significantly increases relapse risk in iTTP patients treated with rituximab. Key risk factors include male sex and prior relapses, with implications for personalized monitoring strategies.

Whole-Genome Sequencing Suggests Casual Community Contact Drives Much of Drug-Resistant Tuberculosis Transmission in Durban
Infectious Diseasescasual contactdrug-resistant tuberculosis

Whole-Genome Sequencing Suggests Casual Community Contact Drives Much of Drug-Resistant Tuberculosis Transmission in Durban

By MedXY|May 9, 2026

A molecular epidemiology study in Durban found that casual community contact, not only household or named contacts, accounted for a substantial share of drug-resistant tuberculosis transmission.

Most Patients Reach 20/40 After Cataract Surgery, but the Current MIPS Success Metric May Misclassify Quality and Exclude Nearly Half of Cases
newsCataract surgeryhealth equity

Most Patients Reach 20/40 After Cataract Surgery, but the Current MIPS Success Metric May Misclassify Quality and Exclude Nearly Half of Cases

By MedXY|May 9, 2026

A large multicenter study found that MIPS measure 191 captures high cataract surgery success rates but excludes many patients and may require case-mix adjustment to support fair surgeon comparisons.

Large Multi-Center EMR Cohort Suggests NSAID Exposure Is Associated With Lower Future Risk of Age-Related Macular Degeneration
newsage-related macular degenerationNSAIDs

Large Multi-Center EMR Cohort Suggests NSAID Exposure Is Associated With Lower Future Risk of Age-Related Macular Degeneration

By MedXY|May 8, 2026

In a large TriNetX retrospective cohort, prescribed NSAID use was associated with a lower subsequent risk of AMD, including both non-exudative and exudative disease, though residual confounding limits causal inference.

HPV Self-Sampling May Expand Cervical Cancer Screening Access for Transmasculine and Nonbinary Patients
newsCervical Cancer Screeningnonbinary patients

HPV Self-Sampling May Expand Cervical Cancer Screening Access for Transmasculine and Nonbinary Patients

By MedXY|Aug 18, 2026

A narrative review suggests HPV self-sampling is acceptable and potentially practice-changing for transmasculine and nonbinary people who are often underscreened for cervical cancer.

Type 1 Diabetes in Sweden Clusters in Rural Areas, With Early-Childhood Geography Showing the Strongest Signal
Diabetes & Endocrinologyearly childhood exposuregeospatial epidemiology

Type 1 Diabetes in Sweden Clusters in Rural Areas, With Early-Childhood Geography Showing the Strongest Signal

By MedXY|May 6, 2026

A nationwide Swedish cohort study found marked geographic variation in type 1 diabetes incidence, with the strongest clustering linked to residential location during the first 5 years of life and higher risk in rural, forested, and agricult

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