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A UK-wide multicentre study shows maternal bivalent RSV prefusion F vaccination reduces infant hospitalisation for RSV-associated ALRI by up to 72%, confirming real-world effectiveness matching clinical trials.
SGLT2 inhibitors adjunct to insulin improve glycemic control, reduce hyperfiltration, and are generally safe in youth with type 1 diabetes under careful ketone monitoring and DKA risk mitigation.
The American Academy of Pediatrics recommends COVID-19 vaccination for all young children aged 6-23 months, diverging from current CDC policies that advise shared decision-making for healthy children. This review analyzes epidemiologic data
Elevated prenatal chlorpyrifos exposure is linked to widespread brain structural abnormalities, reduced neuronal density, and impaired motor functions in children, underscoring the need for exposure minimization during pregnancy.
Fecal microbiota transplantation (FMT) shows promise in improving gastrointestinal and behavioral symptoms in children with autism spectrum disorder (ASD), but further rigorous trials are needed to confirm its efficacy and optimize protocol
Research shows childhood abuse significantly increases the risk of poor adult mental health, with lasting impacts from physical and verbal abuse.
This mixed-methods study assesses a novel Adolescent and Young Adult Healthcare Transition (AYA HCT) clinic that achieved high retention but suboptimal viral suppression among youth with HIV, highlighting key strengths and barriers.
A study links parental workplace exposure to certain chemicals with greater autism severity and functional challenges in children; findings highlight occupational safety and further research needs without proving causation.
In 1,142 patients aged 8–21, a nonrandomized multicenter trial found no clinically meaningful difference in 6-week sonographic stone clearance between ureteroscopy and shockwave lithotripsy; SWL was associated with less pain and fewer misse
The KIWE randomised trial (Lancet Neurol 2023) found no superiority of a classic ketogenic diet over an additional antiseizure medication for seizure frequency in infants (1–24 months) with drug‑resistant epilepsy; tolerability and safety p
Serum metabolome and gut microbiota changes during ketogenic diet therapy correlate with seizure reduction in drug-resistant pediatric epilepsy, implicating plasmalogens and specific gut microbes in anti-seizure effects.
A phase II trial finds that intrathecal autologous bone marrow mononuclear cell therapy combined with education significantly improves core symptoms and adaptive behaviors in young children with ASD compared to education alone.
The first international paediatric bronchiectasis registry highlights significant regional differences in causes, management, and care quality, underscoring urgent needs for harmonized standards and improved multidisciplinary support.
Children are prone to allergic reactions after mosquito or insect bites. This guide explains how to manage symptoms promptly and effectively to prevent complications.
The SHIP AHOY Study demonstrates that even modest elevations in blood pressure during adolescence are linked to a greater burden of subclinical target organ injury, underscoring the importance of early detection and intervention.
Weekly darbepoetin in extremely preterm infants increases red cell mass and reduces transfusion needs, but does not improve cognitive outcomes at 22-26 months’ corrected age.
A randomized trial assessing the impact of Nurse-Family Partnership home visits on child health and utilization over two years found no significant reduction in adverse outcomes but some decrease in emergency department use.
A systematic review and meta-analysis reveals that paternal perinatal depression, anxiety, and stress are associated with adverse developmental outcomes in children, highlighting the need for targeted interventions for fathers during the pe
A multisite RCT found no difference in time to full enteral feeds between donor human milk and formula in moderate to late preterm infants, but formula was associated with faster weight regain.
Despite recommendations for early allergen introduction, peanut intake among US infants remains low, with significant disparities by age and ethnicity. Tree nut and egg consumption trends also reveal notable demographic and temporal differe
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