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In a 9-year OAI cohort analysis, baseline self-reported moderate physical activity was linked to lower knee replacement risk in KL grade 2 but to higher risk in KL >2; high activity showed no clear effect. Results support severity-tailor
In a longitudinal analysis of 4,316 Osteoarthritis Initiative participants, baseline sarcopenia screened by SARC-F and chair-stand testing was associated with accelerated radiographic and symptomatic knee OA progression over 24–48 months an
Emerging evidence supports metformin’s modest pain-relieving effects and potential disease-modifying properties in knee osteoarthritis patients with overweight or obesity, warranting further investigation through larger trials.
A systematic review and meta-analysis finds that reduced patellofemoral contact force within the first year after ACL reconstruction is associated with worse trochlear cartilage structure 1–5 years later; associations for the tibiofemoral j
Two large longitudinal cohorts show baseline chondrocalcinosis is associated with ~75% higher odds of developing radiographic knee osteoarthritis over long-term follow-up, suggesting calcium crystal deposition may be a contributing factor i
A Norwegian registry study reports that 63% of patients with primary ACL injury initially managed non‑operatively remained non‑operative at two years; younger age, participation in pivoting sports and baseline meniscal injury increased risk
An AI-enabled decision aid that generated patient-specific digital twins improved decision quality, reduced decisional conflict and regret, and produced better 6–9 month knee function versus education alone in patients considering total kne
An evidence-based synthesis of the 2025 Cochrane review on fall-prevention in care facilities: which interventions work, for whom, and how to implement them in practice.
A randomized trial shows that physical therapy and text message reminders do not significantly improve knee pain outcomes beyond a simple home exercise program in patients aged 45-85 with degenerative meniscal tears.
This review synthesizes evidence from the RETREAT RCT and past systematic reviews, highlighting that an unsupervised online Tai Chi program significantly improves knee pain and function in knee osteoarthritis, providing a scalable, accessib
This study evaluates the efficacy of vertebral artery reconstruction surgery versus medical therapy in reducing stroke recurrence and improving neurological outcomes over a ten-year period.
Integrating tailored adherence support into exercise rehabilitation for vertebral fragility fractures significantly improves functional mobility and walking capacity compared to standard exercise alone at 12 months.
This meta-analysis evaluates stem cell therapy combined with mechanical support for avascular necrosis of the femoral head, highlighting modest improvements in function and delayed disease progression compared to stem cells alone.
A systematic review and meta-analysis of RCTs indicates Pilates may improve pain and function in knee osteoarthritis patients, though evidence quality is low and safety data insufficient. Caution is warranted in interpreting results, highli
This study examines long-term outcomes of a modern arthroscopic Bankart repair technique for traumatic anterior shoulder instability over a minimum 10-year follow-up, highlighting recurrence rates, risk factors, and functional results.
Methotrexate-induced osteopathy, predominantly affecting postmenopausal women with rheumatoid or psoriatic arthritis, presents as stress fractures in the lower limbs. Early MRI or bone scintigraphy aids diagnosis, and discontinuing methotre
A cluster randomized trial found that enhanced implementation support for group physical therapy in knee osteoarthritis did not significantly improve patient enrollment compared to foundational support, highlighting challenges in fostering
A multisite randomized trial demonstrates that acupuncture, both standard and enhanced, significantly improves chronic low back pain-related disability in older adults compared to usual medical care, with sustained benefits and a favorable
A 4-week anti-inflammatory dietary intervention in knee osteoarthritis patients led to targeted shifts in gut microbiota and metabolite profiles associated with significant pain reduction, highlighting the potential of microbiome-informed n
This article evaluates the prevalence and infection risks associated with combination targeted therapies in adults with psoriatic arthritis, revealing no significant increase in serious or opportunistic infections compared to standard thera
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