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A Sept 22, 2026 Annals of Oncology editorial from Stanford and University of South Carolina authors urges retiring 'negative' oncology names such as triple-negative breast cancer and non-small cell lung cancer in favour of molecularly defined entities, proposing hybrid transitional labels and biology-driven pathology reporting.
This study reveals that lower serum GLP-1 levels are independently associated with endometrial cancer in obese, non-diabetic women, suggesting its potential as a diagnostic biomarker with high sensitivity and specificity.
A decade-long U.S. study demonstrates that uterus transplantation is a viable option for women with absolute uterine factor infertility, showing encouraging surgical safety, promising reproductive outcomes, and generally normal child develo
This review synthesizes current evidence highlighting limitations and opportunities in prenatal care data and metrics, emphasizing the potential of advanced monitoring, targeted interventions, and integrated data systems to improve maternal
A French nationwide cohort study finds first-trimester exposure to second-line glucose-lowering agents, including GLP-1 receptor agonists, is generally safe for pregnancies with type 2 diabetes, though a slight increase in cardiac malformat
A larger surface area of acellular dermal matrix relative to implant size significantly reduces capsular contracture risk following prepectoral implant-based breast reconstruction, with radiotherapy remaining a major risk factor.
A novel sliding adipofascial flap technique in buttock lift surgery preserves hip and upper buttock projection, offering improved aesthetic outcomes with a strong safety profile in 145 female patients.
This study evaluates patient-reported outcomes after minimally invasive breast augmentation (Mia) versus hybrid augmentation, demonstrating superior recovery, pain reduction, and nipple sensitivity with Mia, without compromising satisfactio
This study reveals significant discordance between HER2 scores from endometrial biopsy samples and hysterectomy specimens using gastric scoring criteria, impacting treatment decisions in high-grade endometrial cancer.
Peritoneal fluid-derived small extracellular vesicles exhibit distinct proteomic profiles in endometriosis, identifying potential biomarkers for improved diagnosis independent of cycle phase or disease stage.
Automated insulin delivery (AID) systems, while transformative for type 1 diabetes management, currently lack pregnancy-specific adaptations, leaving a critical gap in care. This article highlights the urgent need to include pregnant women
This article examines how the timing of bilateral salpingo-oophorectomy (BSO) affects the lifetime ovarian cancer risk in women carrying BRCA1 or BRCA2 mutations, emphasizing the benefits of preventive surgery and its residual risk reductio
This clinical trial compares ultrasound-guided transvaginal drainage to laparoscopy for tubo-ovarian abscess evacuation, highlighting differences in cure rates, reintervention frequency, and recovery outcomes.
This phase II study evaluates pembrolizumab combined with carboplatin/paclitaxel and HIPEC in neoadjuvant therapy, followed by pembrolizumab maintenance with or without olaparib in advanced stage III/IV epithelial ovarian cancer patients.
This study identifies key prenatal factors predicting term birth in First Nations nulliparous women and introduces a clinical scoring tool to estimate personalized term birth probabilities, highlighting opportunities for culturally appropri
This study highlights how timing of palliative radiotherapy in gynecologic cancers influences end-of-life care quality, with late radiation associated with less aggressive care and better supportive outcomes compared to radiation administer
A recent study demonstrates the feasibility and safety of hybrid indocyanine green and technetium-99m nanoparticle fluorescence imaging for sentinel lymph node biopsy in early-stage vulvar cancer, improving detection rates and oncologic out
A multicenter prospective study comparing laparoscopic radiofrequency ablation and myomectomy in symptomatic uterine leiomyomas reveals both improve symptoms and quality of life, with myomectomy showing modest but clinically non-significant
A randomized clinical trial found that hip extension at crowning does not reduce significant perineal lacerations during first vaginal deliveries, with no clear benefit over usual flexed positioning.
Escalation of antihypertensive treatment in expectant management of early-onset preeclampsia with severe features correlates with increased maternal adverse outcomes, suggesting treatment trajectory as a dynamic risk indicator.
