Section
This phase 1/2 study evaluates farletuzumab ecteribulin, a folate receptor alpha-targeting ADC, showing that fractionated dosing reduces interstitial lung disease risk and demonstrates preliminary antitumor activity in advanced ovarian, end
Despite menopause being a universal experience, many physicians lack adequate training in menopause care, resulting in unmet patient needs and increased reliance on unregulated sources. Medical education reforms are essential to close this
This review synthesizes recent evidence demonstrating persistent racial and ethnic disparities in treatment initiation and survival among patients with advanced endometrial cancer, highlighting the critical influence of socioeconomic status
A prospective cohort study reveals a lower-than-expected prevalence of uterine fibroids among reproductive-aged Latina women in the US, highlighting age-related risk and associations with reproductive factors.
This retrospective cohort study indicates that menopausal hormone therapy (MHT) is associated with increased risks of strabismus diagnosis and surgery but not reoperation in menopausal women, revealing significant ocular alignment considera
GLP-1 receptor agonists are increasingly used in women of reproductive age, but their safety during periconception and pregnancy remains unclear. Current observational data show no definitive harm, yet robust evidence is lacking, emphasizin
A multicenter RCT demonstrates remote blood pressure monitoring reduces antenatal visits and hospital admissions without compromising maternal or fetal outcomes in women at high risk of preeclampsia.
This article reviews a modified focal excision technique for placenta percreta guided by pathoanatomical defects and neovascularization, demonstrating feasibility and uterus preservation with manageable morbidity in high-grade placenta accr
This article reviews a Phase 1 clinical trial demonstrating the technical feasibility and short-term safety of ultrasound-guided high-intensity focused ultrasound for placental vessel occlusion in early-onset twin-twin transfusion syndrome,
This study assesses the efficacy and safety of pembrolizumab combined with bevacizumab and oral metronomic cyclophosphamide in heavily pretreated platinum-resistant ovarian cancer patients, showing modest disease control with manageable tox
In a large, diverse cohort of women with endometrial cancer, 11.9% harbored pathogenic germline variants, including Lynch syndrome and homologous recombination deficiency-related mutations. Testing at diagnosis identified most Lynch syndrom
This phase III study demonstrates that elagolix is non-inferior to dienogest in reducing moderate-to-severe endometriosis pain, with comparable safety and tolerability profiles, supporting elagolix as a valuable treatment option.
This study reveals that wound complications after second-degree perineal tears or episiotomy significantly increase pelvic floor symptoms, especially affecting sexual function, prolapse, and body image up to 12 months postpartum.
The integration of artificial intelligence in obstetrics and gynecology necessitates clinical competence to ensure patient safety, verify outputs, and maintain physician accountability. Structured training and evaluation are essential for r
This study demonstrates that ovarian-sparing surgery in premenopausal patients with early-stage adult granulosa cell tumors offers survival outcomes similar to bilateral salpingo-oophorectomy, supporting fertility-preserving options in clin
Carrier screening timing and protocols vary widely, often delaying risk assessment and increasing patient distress. Early or prepregnancy screening with concurrent partner testing and thorough counseling improves reproductive decision-makin
A randomized controlled trial demonstrates superior symptom relief with fractional CO2 laser treatment over topical clobetasol in women with vulvar lichen sclerosus, suggesting a novel therapeutic approach.
This retrospective case series evaluates patient-specific pessaries’ success in individuals with prior suboptimal outcomes using standard pessaries for pelvic organ prolapse across Canadian clinical sites.
Individualized cabergoline dosing guided by nadir prolactin levels achieves durable remission and safe pregnancy outcomes in women with prolactinomas, including those resistant or intolerant to bromocriptine.
In early pregnancy, adding oral glucose tolerance testing or continuous glucose monitoring to clinical factors improves prediction of gestational diabetes mellitus but not large-for-gestational-age births.
