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A large study shows oral contraceptives and smoking substantially alter steroid hormone profiles in healthy adults, with implications for disease risk, diagnostics, and treatment decisions.
Resting heart rate is a simple vital sign tied to longevity and cardiovascular risk. Learn what rates are healthiest, why a lower resting heart rate often signals better fitness, how to safely lower it, and when a slow heart rate is a probl
Many common disorders are actually precancerous. Learn the stages of cancer development, six precancerous conditions to watch, their risk factors, tests, and practical prevention and management steps.
Walking and running the same distance deliver similar long-term health gains. Choice should depend on energy expenditure, body type, injury risk, and sustainability—because consistency matters more than speed.
Recent randomized and mechanistic studies provide a nuanced view: metformin shows plausible anti‑aging mechanisms and microbiome‑linked cognitive associations, but randomized trials report no clear anti‑cancer or anti‑senescence effects in
In a randomized, double‑blind crossover trial, a 200 mL anthocyanin‑rich blackcurrant beverage (≈711 mg anthocyanins) taken with a high‑fat meal improved flow‑mediated dilation and reduced agonist‑induced platelet aggregation and IL‑8 over
In a randomized, double‑blind 4‑month trial of middle‑aged overweight adults, oral urolithin A improved hamstring strength (~10–12%), increased peak VO2 and 6‑minute walk distance (clinically meaningful at 33 m for 1,000 mg), altered mitoch
Urolithin A supplementation improved muscle endurance and reduced inflammatory and oxidative stress markers in resistance-trained male athletes over eight weeks, without significant adverse effects.
Recent randomized trials show ashwagandha, including Somin-On™, significantly improves memory and cognitive function in adults with mild cognitive impairment and healthy young adults, with good safety profiles.
A randomized, double‑blind pilot tested an MCT‑supplemented ketogenic diet (MCT‑KD) in 16 people with moderate Parkinson’s disease. The diet was feasible and acceptable, induced nutritional ketosis by day 4, produced metabolic benefits and
The KIWE randomised trial (Lancet Neurol 2023) found no superiority of a classic ketogenic diet over an additional antiseizure medication for seizure frequency in infants (1–24 months) with drug‑resistant epilepsy; tolerability and safety p
A 12-week RCT reveals that ketogenic, but not free-sugar-restricted, diets significantly alter glucose tolerance, lipid metabolism, skeletal muscle phenotype, and gut microbiome in healthy adults, despite similar fat mass reductions.
A 3-week ketogenic diet improved skeletal muscle insulin sensitivity and promoted weight loss in individuals with obesity, without significant effects on liver or adipose tissue insulin sensitivity.
Serum metabolome and gut microbiota changes during ketogenic diet therapy correlate with seizure reduction in drug-resistant pediatric epilepsy, implicating plasmalogens and specific gut microbes in anti-seizure effects.
A head-to-head comparison of ketogenic and Mediterranean diets demonstrates comparable benefits on weight, blood pressure, and metabolic health in overweight hypertensive adults over three months.
Flaxseed powder supplementation shows promise in improving liver fat, lipid metabolism, and inflammation in NAFLD and related metabolic disorders, with effects on gut microbiota but limited synergism with fasting mimicking diets.
This clinical trial compared two modified intermittent fasting strategies to continuous energy restriction for weight loss and insulin resistance improvements in night shift workers, finding no significant differences but overall health ben
A hypercaloric 16:8 time-restricted eating (TRE) regimen supports muscle and strength gains in well-trained individuals, but with modestly lower training volume and squat strength, and less fat mass gain compared to all-day feeding.
Akkermansia muciniphila supplementation improves metabolic outcomes in overweight/obese type 2 diabetes patients only when baseline gut levels are low, underscoring the need for personalized microbiota-guided interventions.
Discover five science-backed, free methods to enhance sleep quality and wake up refreshed—no medication or costly therapies required.
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