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A cluster randomized trial in veterans assessed peer coaching for weight management, showing improved program attendance but no significant 12-month weight loss difference versus enhanced usual care.
A randomized clinical trial demonstrates that personalized high-definition transcranial direct current stimulation (HD-tDCS) significantly improves mood in patients with moderate to severe depression, showing faster and comparable effect si
This trial assessed if videos and infographics from primary care physicians improve flu vaccination rates; overall effects were minimal, but notable improvements occurred in children.
The Smart-T smartphone intervention significantly improves 7-day smoking abstinence at 26 weeks in low-income adults, outperforming the standard QuitGuide app when combined with nicotine replacement therapy.
A 4-week randomized trial shows that low-dose cannabidiol (CBD) may cause transient liver enzyme elevations in healthy adults, emphasizing the need for vigilance and further safety assessment of consumer CBD products.
This review synthesizes recent evidence from the ACTIV-6 trial showing metformin does not significantly reduce symptom duration in low-risk adults with COVID-19, addressing safety, clinical outcomes, and translational insights.
A randomized clinical trial in Uganda compared standard open anterior mesh repair with a modified technique addressing femoral hernias, demonstrating both methods as safe and effective options for women’s groin hernia repair in low-re
A randomized clinical trial in South Australian long-term care facilities found germicidal UV light appliances did not significantly reduce acute respiratory infection rates per cycle but modestly lowered total infections over time, suggest
A large pragmatic trial demonstrates that daily emollient application starting before 9 weeks of age significantly reduces the risk of atopic dermatitis by 24 months in infants not selected for high risk, offering a feasible preventive appr
A randomized trial demonstrates that iodine-impregnated drapes significantly reduce pocket contamination and cardiac implantable electronic device infections in repeat surgeries, offering a simple, cost-effective prophylactic intervention.
A randomized clinical trial demonstrates that varenicline, combined with behavioral counseling, markedly improves nicotine vaping cessation rates in youth aged 16-25 who vape daily and do not regularly smoke tobacco.
A multicenter phase 3 trial demonstrates that sequential chemoradiotherapy is noninferior to induction plus concurrent chemoradiotherapy for stage III/IVA nasopharyngeal carcinoma with fewer acute toxicities.
Smartphone-delivered cognitive-behavioral therapy (CBT) via a digital therapeutic app significantly reduces recurrent suicide attempts and sustains reduction in suicidal ideation among adults with prior suicide attempts.
This review analyzes a randomized clinical trial comparing modern pain neuroscience approach and usual care physiotherapy in chronic whiplash disorders, highlighting immediate and 12-month improvements, cost-effectiveness, and benefits in a
