Personalized High-Definition Transcranial Direct Current Stimulation: A Promising Rapid Intervention for Moderate to Severe Depression
Highlight
– Personalized HD-tDCS significantly reduces depressive symptoms in moderate to severe depression compared to sham control.
– Effect size (-0.50) observed after 12 sessions is comparable to pharmacotherapy and psychotherapy but with faster onset.
– HD-tDCS is well-tolerated, causing only mild adverse effects.
– Exploratory findings suggest concurrent reduction in anxiety symptoms associated with active HD-tDCS treatment.
Study Background and Disease Burden
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.