Smart-T Digital Intervention Enhances Smoking Cessation Among Low-Income Adults: Insights from a Randomized Clinical Trial

Highlight

• A tailored just-in-time adaptive intervention (Smart-T) significantly increased biochemically verified 7-day smoking abstinence at 26 weeks compared to a standard QuitGuide app in low-income adults.
• Smart-T users interacted more frequently with the intervention and rated it as more helpful than QuitGuide users.
• Both interventions were combined with nicotine replacement therapy, underscoring the added value of the adaptive smartphone support.
• No significant differences were observed for 30-day or continuous abstinence outcomes, indicating the need for further optimization of sustained cessation support.

Study Background and Disease Burden