Tag
A study reveals a significant secular increase in islet autoimmunity incidence among Colorado children from 1993 to 2010, particularly in those with moderate-risk HLA genotypes, highlighting evolving risk profiles beyond known environmental
This review synthesizes evidence linking cumulative atopic diseases—including asthma, atopic dermatitis, and allergic rhinitis—to keratoconus risk, highlighting a dose-dependent association and the role of healthcare utilization in case asc
Accumulating evidence underscores how adverse social determinants of health (SDOH) from early adulthood heighten the risk of early-onset stroke, with dose-dependent effects and disparities by race and sex.
A comprehensive multinational study reveals that achalasia significantly raises the risk of esophageal squamous cell carcinoma independently, while its association with adenocarcinoma is modest and largely mediated by gastroesophageal reflu
This study reveals that acute hypoxemic respiratory failure (AHRF) affects half of ICU patients needing respiratory support, with severity linked to worse outcomes. Lung-protective ventilation is common, underscoring the need for standardiz
Norwegian cohort data reveal no protective effect of rotavirus vaccination against type 1 diabetes onset in early childhood, clarifying prior conflicting findings.
This review synthesizes key epidemiologic evidence linking transfusion-related allergic reactions with alpha-gal syndrome (AGS), revealing significant risk in blood type O recipients of B or AB plasma/platelets in AGS-endemic regions.
This review synthesizes nationwide epidemiological trends of sepsis in South Korea from 2011 to 2022, elucidating incidence increases, declining in-hospital mortality, and key clinical and socioeconomic mortality determinants alongside rele
This study reveals a high heart failure risk within 5 years of diabetes diagnosis, highlighting insulin resistance and reduced kidney function as independent predictors beyond conventional risk factors.
This retrospective EBMT study identifies secondary autoimmune and inflammatory diseases as rare but significant complications following allo-HSCT, highlighting their incidence, risk factors, and impact on patient survival, calling for impro
A nationwide Danish study links prolonged residential road traffic noise exposure with increased Parkinson disease risk, highlighting the protective effect of having a quiet building facade.
A large sibling-matched cohort study found no link between prenatal acetaminophen exposure and autism or ADHD, suggesting prior associations were confounded by familial factors and supporting the safety of indicated paracetamol use during p
This study examines how obesity and alcohol consumption jointly impact diabetes risk over time in an Asian cohort, highlighting differences in interaction measures and implications for diabetes prevention.
Analyzing 54 million adults in England reveals rising obesity rates from 2019-2025, disproportionately affecting socioeconomically deprived, ethnic minority, and younger adult groups, with widening inequalities intensified during the COVID-
This review synthesizes evidence on the prevalence, incidence, and prognosis of cancer and heart failure comorbidity in Scotland, integrating recent cohort data and cardio-oncology research to inform clinical practice and future research di
The PURE study reveals significant global disparities in heart failure incidence and mortality, with hypertension as the leading modifiable risk factor, highlighting the need for targeted prevention and treatment strategies.
A landmark population-based study spanning 2006-2020 in Stockholm, Sweden, reveals that biochemically confirmed primary hyperparathyroidism incidence increased by 52% while only half of affected patients received clinical diagnosis, highlig
This review analyzes a decade-long nationwide study on TB after Allo-HSCT in France, revealing a 60/100,000 incidence rate, high extrapulmonary involvement, and the critical need for screening patients from high-incidence regions.
The 2024 National Firearms Survey reveals that 29.8 million US adults acquired firearms between 2021 and 2024. This trend introduced 11.2 million new owners, significantly increasing household exposure for millions of adults and children, r
By 2050, global gastrointestinal cancer incidence is projected to surge by 85%, reaching 9.06 million cases annually. While gastric cancer rates are declining, colorectal and pancreatic cancers are rising sharply, particularly in low and me
