Introduction
The growing global population of older adults, defined as those aged 60 years or more, presents complex challenges for healthcare systems worldwide. Older adults typically have multimorbidity and are frequently prescribed multiple medications, known as polypharmacy, elevating the risk of adverse drug reactions, drug interactions, and medication nonadherence. Recently published insights emphasize integrating exercise prescriptions into medication management as an innovative, holistic approach to optimize health outcomes in geriatric care. This article critically examines the rationale, evidence, and practical considerations underpinning this strategy to enhance therapeutic efficacy, minimize the harms of polypharmacy, and improve functional status among older adults.


