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Polypharmacy Challenges in Older Adults with Metabolic Dysfunction-Associated Steatotic Liver Disease: Navigating Care in a High-Risk Population
Gastroenterologycardiometabolic diseasesMASLD

Polypharmacy Challenges in Older Adults with Metabolic Dysfunction-Associated Steatotic Liver Disease: Navigating Care in a High-Risk Population

By MedXY|Jul 17, 2026

Older adults with MASLD, especially those aged 75 and above, experience a high burden of polypharmacy linked to multimorbidity, necessitating careful medication management to balance disease control and geriatric vulnerabilities.

SGLT2 Inhibitors Reduce Gout-Related Medication Burden in Patients with Type 2 Diabetes
Diabetes & Endocrinologygout
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polypharmacy

SGLT2 Inhibitors Reduce Gout-Related Medication Burden in Patients with Type 2 Diabetes

By MedXY|Mar 6, 2026

A large-scale target trial emulation study demonstrates that SGLT2 inhibitors significantly reduce the initiation of allopurinol and the use of anti-inflammatory medications in patients with comorbid gout and type 2 diabetes, offering a pot

Behavioral Science-Integrated EHR Prompts Significantly Increase Deprescribing Rates for Older Adults: A Randomized Clinical Trial
Family Medicine & NutritiondeprescribingElectronic Health Records

Behavioral Science-Integrated EHR Prompts Significantly Increase Deprescribing Rates for Older Adults: A Randomized Clinical Trial

By MedXY|Jan 30, 2026

This randomized clinical trial demonstrates that EHR-based behavioral interventions, such as precommitment and boostering prompts, significantly improve deprescribing rates for potentially inappropriate medications in older adults, providin

Integrating Exercise and Medication Management in Geriatric Care: A Holistic Approach to Improve Health Outcomes and Reduce Polypharmacy
Internal Medicineexercise therapygeriatrics

Integrating Exercise and Medication Management in Geriatric Care: A Holistic Approach to Improve Health Outcomes and Reduce Polypharmacy

By MedXY|Oct 20, 2025

Integrating exercise prescriptions with medication management offers a holistic strategy to optimize health, reduce polypharmacy, and mitigate adverse effects in older adults, enhancing their functional status and quality of life.

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