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This study highlights that geriatric vulnerabilities and comorbidities, once considered nonmodifiable, play a dominant role in 30-day readmissions after colorectal surgery in older adults, emphasizing the need for integrated perioperative i
This secondary analysis of the DANFLU-2 trial demonstrates that high-dose influenza vaccines provide superior protection against cardiorespiratory and cardiovascular hospitalizations in older adults with diabetes, particularly those with a
A secondary analysis of the DANFLU-2 trial confirms that high-dose influenza vaccine significantly reduces cardiorespiratory hospitalizations in older adults with diabetes, with potentially enhanced benefits for those with longer disease du
A comprehensive meta-analysis of 121.8 million individuals confirms that RSV vaccines are approximately 75% effective against hospitalization and severe disease in older adults, despite low global uptake and a rare risk of Guillain-Barré sy
A 10-year follow-up of the ASPREE trial reveals that low-dose aspirin does not reduce cancer incidence in adults aged 70 and older, but is associated with increased cancer-related mortality, challenging long-held assumptions about aspirin&#
A post hoc analysis of the ASPREE trial reveals that heart stress, measured by NT-proBNP, significantly alters the relationship between blood pressure and cardiovascular risk in older adults, suggesting a paradigm shift toward biomarker-gui
A large-scale cross-sectional study of 51,202 admissions reveals that 35.6% of patients aged 70 and older experience cognitive morbidity, predominantly delirium. The findings underscore the urgent necessity for hospital-wide screening and m
A large-scale longitudinal study reveals that ICU survivors aged 60–79 face significantly higher 5-year excess mortality and functional decline compared to the general population, whereas outcomes for nonagenarians converge with their peers
A multicenter randomized trial reveals that a brief, structured training intervention for emergency physicians significantly increases the use of ultrasound-guided fascia iliaca blocks, resulting in a 28% reduction in delirium risk for geri
The DANFLU-2 trial found that while high-dose influenza vaccines significantly reduced influenza-specific hospitalizations in older adults, they did not reach statistical significance for the combined primary endpoint of influenza or pneumo
Integrating exercise prescriptions with medication management offers a holistic strategy to optimize health, reduce polypharmacy, and mitigate adverse effects in older adults, enhancing their functional status and quality of life.
