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This review synthesizes current evidence on adalimumab, secukinumab, and bimekizumab for moderate-to-severe hidradenitis suppurativa, emphasizing clinical efficacy, safety, mechanistic insights, and cost-effectiveness across diverse health
Longitudinal monitoring reveals that persistence and growth dynamics of peripheral globules in melanocytic lesions predict melanoma risk more accurately than static features alone, informing tailored surveillance strategies.
Enfortumab vedotin (EV) therapy in advanced urothelial carcinoma is frequently associated with cutaneous adverse events (cAEs). These EV-induced skin toxicities correlate independently with improved progression-free and overall survival, ev
A multicenter prospective real-world study in China evaluated treatment outcomes of tinea capitis, highlighting itraconazole’s superior efficacy over terbinafine for certain fungal strains like Microsporum canis, informing optimized a
Early results from the RESET-PV trial indicate that CD19 CAR T-cell therapy without lymphodepleting preconditioning is feasible and safe for pemphigus vulgaris, offering significant clinical improvement and durable B-cell depletion.
Oral nicotinamide reduces keratinocyte carcinoma incidence in high-risk individuals, providing significant cost savings and quality-adjusted life-year gains, supporting its role as a cost-effective preventive strategy.
Reflectance confocal microscopy (RCM) combined with dermoscopy significantly improves detection and management of equivocal pigmented macules on the head and neck, reducing missed malignancies and overtreatment in a study of 2006 lesions.
A digital standardized skin care regimen improves clearance rates, reduces relapse, and enhances quality of life in acne-rosacea comorbidity, mediated partially by epidermal barrier restoration.
A multicenter cohort study demonstrates that circulating tumor DNA (ctDNA) is more accurate than Merkel cell polyomavirus (MCPyV) antibody testing in detecting recurrence of Merkel cell carcinoma, improving patient surveillance and risk str
This cohort study reveals differential melanoma survival outcomes linked to institutional settings and insurance types, highlighting the need for standardized care in advanced melanoma stages.
This article addresses common patient misconceptions about hyaluronic acid fillers, elucidating safety, efficacy, and best practice strategies to ensure natural results and improved patient trust.
This article reviews a retrospective study evaluating the feasibility and outcomes of a 24-week abrocitinib tapering regimen in moderate-to-severe atopic dermatitis, comparing dose reduction versus interval extension approaches and their im
A multidisciplinary Delphi panel offers practical, consensus-based recommendations to standardize when and how to use staging and surveillance imaging for localized cutaneous squamous cell carcinoma (CSCC).
This study evaluates the successful 24-week tapering of abrocitinib in moderate-to-severe atopic dermatitis patients, comparing dose reduction versus interval extension tapering regimens and demonstrating high feasibility with substantial d
This retrospective analysis demonstrates high-frequency ultrasound’s efficacy in diagnosing palpable indurations post-cosmetic filler injection, enabling tailored treatment strategies that improve clinical outcomes and minimize intervention
A large meta-analysis found JAK-STAT inhibitors slightly increased influenza, bronchitis, and herpes zoster risk, especially in atopic dermatitis, while serious and opportunistic infections were not significantly increased.
In this multicentre cohort of 207 hospitalized adults with DRESS, 17% required ICU care. Hospital-acquired DRESS and greater clinical severity independently predicted ICU admission, while ICU mortality reached 20%.
A single-center validation study suggests the CTCL-PRO-20 may provide a reliable, disease-specific measure of quality of life in patients with cutaneous T-cell lymphoma.
This article provides an in-depth exploration of scrotal lymphedema and hyperhidrosis, detailing their physiological causes, clinical symptoms, and the latest management strategies for both patients and healthcare providers.
A pilot randomized controlled trial and translational study demonstrate that Sopoongsan (SPS) effectively reduces chronic upper body pruritus in atopic and seborrheic dermatitis by inhibiting STAT1-mediated inflammatory pathways, offering a
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