Rapid Isolation of Epidermal Stem Cells Enhances Single-Stage Composite Skin Graft Outcomes for Full-Thickness Wounds

Highlight

– The study demonstrates successful intraoperative isolation of autologous epidermal stem cells (ESCs) using Myseed technology from split-thickness skin grafts (STSGs).
– Incorporating ESCs into acellular dermal matrix (ADM) composite grafts significantly enhances vascularization and graft survival in full-thickness wounds.
– Single-stage tissue-engineered skin (TES) application reduces wound contraction and accelerates healing compared to traditional STSG and ADM-STSG composite grafts.

Study Background