Xenotransplantation: Bridging the Gap in Liver Transplantation with Genetically Modified Pig Organs

Highlight

• Genetically modified pig-to-baboon liver xenotransplantation demonstrates survival beyond 4 weeks as a bridge therapy for acute liver failure.
• Xenotransplantation research must carefully balance scientific progress with ethical considerations, favoring academic and government oversight over commercial dominance.
• Regulatory frameworks, including expert committees, are critical to ensure patient safety and equitable clinical implementation.
• Public opinion studies reveal broad acceptance of xenotransplantation across diverse populations, emphasizing need to focus on research direction and regulation rather than societal hesitation.

Study Background