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A randomized trial demonstrates that using an autologous anterior lens capsule as an intrascleral spacer during deep sclerectomy combined with phacoemulsification lowers intraocular pressure and enhances surgical success in glaucoma patient
A cohort study identifies key risk factors such as faster baseline visual field loss, higher post-progression intraocular pressure, and older age that predict recurrence of visual field progression in glaucoma, emphasizing the need for pers
Lower systemic blood pressure, especially minimum values measured over 24 hours, is associated with accelerated retinal nerve fiber layer loss in primary open-angle glaucoma, highlighting the prognostic value of ambulatory BP monitoring.
This review synthesizes recent evidence on event-based progression detection in glaucoma, highlighting that OCTA vessel density may identify progression earlier than structural OCT or visual field testing, with important implications for cl
A 10-year Korean cohort study reveals that retinal arteriosclerosis, intraocular pressure, age, serum uric acid, and cholesterol levels significantly increase the risk of structural glaucoma conversion.
A stress test measuring intraocular pressure identifies glaucoma patients at risk of rapid progression despite normal office pressure readings, offering complementary prognostic insights beyond routine checks.
This study evaluates long-term outcomes of selective laser trabeculoplasty (SLT) in controlling intraocular pressure and preventing visual field deterioration, identifying clinical factors influencing effectiveness and progression risk.
The TAGS Study shows trabeculectomy slows visual field loss more effectively than medical treatment in advanced glaucoma, yet this did not translate into significant quality-of-life improvements over five years, highlighting limitations in
This study assesses the added value of 10-2 visual field testing compared to the 24-2 test in detecting progression of early glaucoma, highlighting its role in patients with localized central visual field loss.
This multicenter study validates prespecified OCT diagnostic rules demonstrating high accuracy in detecting glaucomatous optic neuropathy in nonpathologic myopic eyes, offering improved clinical decision support across diverse populations.
This study compares diagnostic-only versus combined diagnostic and treatment-based definitions of glaucoma in UK Biobank participants, revealing stronger associations of risk factors and severity biomarkers with definitions including treatm
A double-blind randomized trial found that a single intraoperative intravitreal bevacizumab injection improved 3-year trabeculectomy survival and reduced postoperative medication needs versus placebo.
In a large retrospective glaucoma cohort, delayed follow-up was common yet was not generally associated with visual field worsening, although longer delays appeared more consequential in eyes with worse baseline visual field loss.
A 6-month personalized coaching program (SEE) significantly improved glaucoma medication adherence by 19.7% compared to standard education, reducing vision loss risk in a randomized trial of 235 patients.
Study reveals significant links between optic nerve head structural changes and choroidal microvascular dropout in glaucomatous eyes, particularly in myopia. Deep structural parameters like neural canal geometry strongly correlate with micr
A 19-year retrospective study reveals that microvascular dropout and β-zone parapapillary atrophy progression are powerful independent predictors of structural optic disc damage in glaucoma suspects, even when visual fields remain stable.
A retrospective cohort study reveals that microvascular dropout (MvD) and β-zone parapapillary atrophy (PPA) progression are significant independent predictors of structural optic disc damage in glaucoma suspect eyes, identifying risk long
The SEE randomized clinical trial demonstrates that a 6-month personalized coaching program using motivational interviewing significantly improves glaucoma medication adherence and reduces patient distress compared to standard education.
A multicenter cohort study of 1.8 million clinic encounters reveals that while clinicians view intraocular pressure as a continuous risk factor, the historical 22 mm Hg cutoff remains a significant psychological trigger for escalating glauc
A Cochrane review of 22 cohort studies (6,082 patients) found bilateral disease, disc haemorrhage, female sex, and active treatment have the most consistent associations with visual-field progression in open-angle glaucoma, but overall evid
