Microvascular Dropout as a Potent Biomarker for Structural Progression in Glaucoma Suspects

High-Risk Indicators in Glaucoma Suspects: The Role of Microvascular Dropout

Identifying which glaucoma suspects will eventually progress to manifest glaucoma remains one of the most significant challenges in clinical ophthalmology. While intraocular pressure (IOP) remains the only modifiable risk factor, structural changes often precede functional loss by years. Recent research published in the American Journal of Ophthalmology by Soltani et al. provides compelling evidence that microvascular dropout (MvD) in the parapapillary region is a critical biomarker for structural optic disc progression, even in eyes that remain clinically stable by traditional perimetric standards.

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