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Prediabetes Remission Without Weight Loss: Rethinking Targets to Prevent Type 2 Diabetes

MedXY Editorial Team•Nov 12, 2025•Diabetes & Endocrinology
diabetes preventionprediabetesremission

Highlight

– Prediabetes remission (return to normal glucose regulation) can be achieved without overall weight loss and substantially reduces progression to type 2 diabetes (T2D).

– Mechanisms include improved insulin sensitivity, enhanced β‑cell function and increased β‑cell responsiveness to GLP‑1, with differential adipose redistribution (subcutaneous instead of visceral).

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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