We use cookies

Our website uses essential cookies and, with your consent, additional cookies to measure performance and improve our services. Cookie Policy.

You can change your choice at any time.

MMedXYNews
HomeVideos
MedXY AI/MedXY News/Section: Critical Care

Paracetamol Lowers Cerebral Temperature Modestly but Meaningfully in Febrile Brain‑Injured Patients: Results of the NEUROTHERM Randomized Pharmacodynamic Trial

MedXY Editorial Team•Dec 9, 2025•Critical Care
critical carefeverparacetamol

Highlight

– A single intravenous dose of paracetamol reduced mean cerebral temperature (CT) by 0.6°C versus placebo over 6 hours in febrile brain‑injured patients (n = 99).

– Paracetamol maintained CT <38.5°C for a median 215 minutes vs. 0 minutes with placebo; however, ~30% of treated patients were nonresponders.

MedXY registered readers

Sign in free to continue reading

Create or use your MedXY account to unlock the complete article.

This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

Related articles

Open language-specific specialty feeds and department pages.

Unlocking the Potential of Novel Biomarkers for Acute Kidney Injury in the Critically Ill: A Comprehensive Evidence MappingThis article reviews over 1100 studies on novel biomarkers for acute kidney injury (AKI) in critically ill patients, highlighting their predictive, diagnostic, and management roles while identifying gaps for future clinical implementation.Sep 18, 2026Extracorporeal Membrane Oxygenation without Mechanical Ventilation in ARDS: Insights from an International Cohort StudyThis study evaluates ECMO as a standalone respiratory support in ARDS patients avoiding invasive mechanical ventilation, highlighting outcomes, strategy failures, and mortality implications.Sep 17, 2026Evolving Critical Care Needs and Outcomes in Andes Virus-Associated Hantavirus Cardiopulmonary Syndrome: Insights from a National Chilean CohortThis study evaluates respiratory support and mortality trends in Andes virus-induced hantavirus cardiopulmonary syndrome (HCPS) across Chile, highlighting increased mortality during the COVID-19 pandemic period and a high requirement for inSep 13, 2026
Loading comments...
MedXY briefing

Get the free newsletter

Evidence-led clinical news, trends, and analysis—delivered to your inbox.

Ask MedXY AI

Most popular

Intimate Health
Five Benefits for Women Continuing Sexual Activity After Menopause
Intimate Health
Why Some Women Have a Strong Sex Drive—And Why Men Shouldn't Worry About It
Nursing &amp; care
How often should a couple have sex?
Intimate Health
Classic Intimacy Recommendations: How to Help Women Reach Orgasm and Enjoy Mutual Pleasure
Intimate Health
What Makes a Woman "Physiologically Addicted" Is Never Money, But These Two Relationship Qualities
© 2026 MedXY
Contact usAbout usPrivacy PolicyMedXY story
Navigating Rehabilitation During ECMO Support: Insights from a Retrospective Cohort Study
This study explores rehabilitation initiation, progression, and physical activity levels in adult ECMO patients, highlighting early active rehabilitation feasibility and varied activity trajectories based on clinical goals.
Sep 5, 2026
Bridging the Gap: Gender Disparities in Critical Care Authorship Across Economic ContextsThis bibliometric study reveals persistent gender disparities in authorship of critical care publications, with women better represented in low- and middle-income countries and a modest increase in female authorship from 2018 to 2022 globalAug 25, 2026
Inflammatory Phenotypes in Severe Pneumonia: Bridging Clinical Insights and Mouse Models for Targeted TherapiesThis article explores hyperinflammatory and hypoinflammatory phenotypes in severe pneumonia, their clinical impact, and translational mouse models that inform precision therapeutic strategies.Aug 23, 2026