Does Anticoagulation After Successful AF Ablation Matter? The OCEAN Trial Shows No Clear Advantage of Rivaroxaban over Aspirin
Highlight
– In the randomized OCEAN trial (n=1284), rivaroxaban (15 mg daily) did not significantly reduce a composite of stroke, systemic embolism, or new covert embolic stroke on MRI compared with aspirin over 3 years.
– Event rates were low in both arms (0.31 vs 0.66 events per 100 patient‑years), producing wide confidence intervals and limited statistical power for modest differences.
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