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Insulin Resistance and Hyperinsulinemia: The Hidden Drivers of Lung Function Decline in Diabetes

MedXY Editorial Team•Mar 20, 2026•Diabetes & Endocrinology
diabetesFEV1insulin resistancePulmonary function

Highlights

1. Reduced lung function, characterized by lower FEV1 and FVC, is significantly associated with systemic insulin resistance and impaired insulin clearance across the diabetes spectrum.

2. Mendelian randomization (MR) analysis provides evidence for a causal relationship between HOMA-insulin resistance (HOMA-IR) and decreased FEV1.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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