Immune-related adverse events strongly predict early graft rejection after liver transplant in HCC patients treated with checkpoint inhibitors
Highlights
Patients with immune-related adverse events (irAEs) during pretransplant immune checkpoint inhibitor (ICI) therapy had a markedly higher odds of post‑transplant liver allograft rejection (OR 9.17).
A short washout period from last ICI dose to transplantation (<30 days) and recipient age under 40 years were additional independent risk factors; a multivariable model showed acceptable discrimination (AUC 0.788).
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.