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Transplantation

Serum LRG-1 and Citrulline Ratio: A Breakthrough Biomarker Duo for Intestinal Transplant Rejection Monitoring

Combining serum leucine-rich alpha-2-glycoprotein 1 (LRG-1) with citrulline offers a sensitive, noninvasive biomarker strategy for early detection and monitoring of rejection in intestinal transplantation, potentially reducing reliance on i

Nov 3, 2026
Gastroenterology

Immune-related adverse events strongly predict early graft rejection after liver transplant in HCC patients treated with checkpoint inhibitors

A multicentre retrospective cohort found that pretransplant immune-related adverse events (irAEs) markedly increase the risk of early liver allograft rejection after liver transplantation for hepatocellular carcinoma (HCC). IrAEs, short ICI

Nov 6, 2025Sign in to read
Internal Medicine

Balancing Efficacy and Safety: Immune Checkpoint Inhibitors in Solid Organ Transplant Recipients with Advanced Cancers

This systematic review and meta-analysis evaluate cancer and graft outcomes in transplant recipients treated with immune checkpoint inhibitors, revealing differences by cancer type and potential strategies to reduce rejection risk.

Oct 27, 2025Sign in to read

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